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Cryo-EM structure of human Peroxisomal ABC Transporter ABCD1

Electron Microscopy
3.35Å resolution
PDB entry 7yrq coloured by chain, front view.
PDB entry 7yrq coloured by chain, side view.
PDB entry 7yrq coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: ATP-binding cassette sub-family D member 1
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Multimeric state: homo dimer
Accessible surface area: 58696.64 Å2
Buried surface area: 11818.03 Å2
Dissociation area: 5,909.02 Å2
Dissociation energy (ΔGdiss): 92.09 kcal/mol
Dissociation entropy (TΔSdiss): 17.07 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-152660

Macromolecules

ATP-binding cassette sub-family D member 1
Chains: A, B
Length: 745 amino acids
Theoretical weight: 83.04 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P33897 (Residues: 1-745; Coverage: 100%)
Gene names: ABCD1, ALD
Pfam:
InterPro:
ATP-binding cassette sub-family D member 1 in PDB entry 7yrq, assembly 1, front view.
ATP-binding cassette sub-family D member 1 in PDB entry 7yrq, assembly 1, side view.
ATP-binding cassette sub-family D member 1 in PDB entry 7yrq, assembly 1, top view.
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