Function and Biology Details
Reactions catalysed:
A beta-D-glucuronoside + H(2)O = D-glucuronate + an alcohol
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-210862 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Klotho
Molecule details ›
Chain: A
Length: 942 amino acids
Theoretical weight: 108.4 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Glycosyl hydrolase family 1
Length: 942 amino acids
Theoretical weight: 108.4 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q9UEF7 (Residues: 34-975; Coverage: 96%)
Sequence domains: Glycosyl hydrolase family 1
Fibroblast growth factor receptor 3
Molecule details ›
Chains: C, E
Length: 211 amino acids
Theoretical weight: 23.36 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 211 amino acids
Theoretical weight: 23.36 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P22607 (Residues: 148-358; Coverage: 27%)
Sequence domains:
Fibroblast growth factor 23 N-terminal peptide
Molecule details ›
Chain: B
Length: 179 amino acids
Theoretical weight: 20.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Fibroblast growth factor
Length: 179 amino acids
Theoretical weight: 20.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q9GZV9 (Residues: 25-203; Coverage: 79%)
Sequence domains: Fibroblast growth factor
