› 7yuv

Electron Microscopy
3.8Å resolution

MtaLon-ADP for the spiral oligomers of tetramer

Released:
DOI: 10.2210/pdb7yuv/pdb
PDB entry 7yuv coloured by chain, front view.
PDB entry 7yuv coloured by chain, side view.
PDB entry 7yuv coloured by chain, top view.
Source organism: Meiothermus taiwanensis
Primary publication:
A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Li S, Hsieh KY, Kuo CI, Lin TC, Lee SH, Chen YR, Wang CH, Ho MR, Ting SY, Zhang K, Chang CI
Nat Commun 14 7340 (2023)
PMID: 37957149
Related structures: EMD-34112

Function and Biology Details

Reaction catalysed: 
Hydrolysis of proteins in presence of ATP.
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-232514 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lon protease Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 793 amino acids
Theoretical weight: 88.55 KDa
Source organism: Meiothermus taiwanensis
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: A0A059VAZ3 (Residues: 1-793; Coverage: 100%)
Gene names: Mcate_02015, lon, lon1_1, lonA1
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand ADP 3 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.8Å
Relevant EMDB volumes: EMD-34112
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'

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