7yxw

X-ray diffraction
2.5Å resolution

Structure of the p22phox A200G mutant in complex with p47phox peptide

Released:
Model geometry
Fit model/data

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-146610 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cytochrome b-245 light chain Chain: D
Molecule details ›
Chain: D
Length: 18 amino acids
Theoretical weight: 1.93 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P13498 (Residues: 151-168; Coverage: 9%)
Gene name: CYBA
Neutrophil cytosol factor 1 Chain: A
Molecule details ›
Chain: A
Length: 131 amino acids
Theoretical weight: 14.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P14598 (Residues: 156-285; Coverage: 33%)
Gene names: NCF1, NOXO2, SH3PXD1A
Sequence domains: SH3 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P41212
Unit cell:
a: 102.444Å b: 102.444Å c: 56.075Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.243 0.241 0.269
Expression systems:
  • Not provided
  • Escherichia coli