7yzp

Electron Microscopy
4Å resolution

Hairpin-bound state of the E. coli Mre11-Rad50 (SbcCD) head complex bound to ADP and a DNA hairpin

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-122358 (preferred)
Entry contents:
2 distinct polypeptide molecules
1 distinct DNA molecule
Macromolecules (3 distinct):
Nuclease SbcCD subunit D Chains: A, B
Molecule details ›
Chains: A, B
Length: 407 amino acids
Theoretical weight: 45.64 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0AG76 (Residues: 1-400; Coverage: 100%)
Gene names: JW0388, b0398, sbcD, yajA
Sequence domains:
Nuclease SbcCD subunit C Chains: C, D
Molecule details ›
Chains: C, D
Length: 1048 amino acids
Theoretical weight: 118.85 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P13458 (Residues: 1-1048; Coverage: 100%)
Gene names: JW0387, b0397, rmuA, sbcC
Sequence domains:
DNA hairpin (59-MER) Chain: F
Molecule details ›
Chain: F
Length: 75 nucleotides
Theoretical weight: 23.14 KDa

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution:
Relevant EMDB volumes: EMD-14393
Expression system: Escherichia coli