Function and Biology Details
Reactions catalysed:
ATP + methylphosphonate = alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine
Alpha-D-ribose 1-methylphosphonate 5-phosphate + S-adenosyl-L-methionine + reduced electron acceptor = alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + methane + L-methionine + 5'-deoxyadenosine + electron acceptor
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase
- Bacterial phosphonate metabolism, PhnH
- ABC transporter-like, ATP-binding domain
- P-loop containing nucleoside triphosphate hydrolase
- ATP-binding protein PhnK
- Phosphonate metabolism protein PhnI
- PhnH-like superfamily
- Phosphonate metabolism PhnG
3 more domains
Structure analysis Details
Assembly composition:
hetero decamer (preferred)
PDBe Complex ID:
PDB-CPX-147795 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG
Molecule details ›
Chains: A, E
Length: 150 amino acids
Theoretical weight: 16.55 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Phosphonate metabolism protein PhnG
Length: 150 amino acids
Theoretical weight: 16.55 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P16685 (Residues: 1-150; Coverage: 100%)
Sequence domains: Phosphonate metabolism protein PhnG
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH
Molecule details ›
Chains: B, F
Length: 194 amino acids
Theoretical weight: 21.05 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains: Bacterial phosphonate metabolism protein (PhnH)
Length: 194 amino acids
Theoretical weight: 21.05 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical: P16686 (Residues: 1-194; Coverage: 100%)
Sequence domains: Bacterial phosphonate metabolism protein (PhnH)
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI
Molecule details ›
Chains: C, G
Length: 354 amino acids
Theoretical weight: 38.95 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains: Bacterial phosphonate metabolism protein (PhnI)
Length: 354 amino acids
Theoretical weight: 38.95 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical: P16687 (Residues: 1-354; Coverage: 100%)
Sequence domains: Bacterial phosphonate metabolism protein (PhnI)
Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase
Molecule details ›
Chains: D, H
Length: 281 amino acids
Theoretical weight: 31.89 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains: Phosphonate metabolism protein PhnJ
Length: 281 amino acids
Theoretical weight: 31.89 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical: P16688 (Residues: 1-281; Coverage: 100%)
Sequence domains: Phosphonate metabolism protein PhnJ
Putative phosphonates utilization ATP-binding protein PhnK
Molecule details ›
Chains: I, J
Length: 291 amino acids
Theoretical weight: 32 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 291 amino acids
Theoretical weight: 32 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical: P16678 (Residues: 1-252; Coverage: 100%)
Sequence domains:
