› 7z2r

X-ray diffraction
2.57Å resolution

Differences between the GluD1 and GluD2 receptors revealed by GluD1 X-ray crystallography, binding studies and molecular dynamics

Released:
DOI: 10.2210/pdb7z2r/pdb
PDB entry 7z2r coloured by chain, front view.
PDB entry 7z2r coloured by chain, side view.
PDB entry 7z2r coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Differences between the GluD1 and GluD2 receptors revealed by GluD1 X-ray crystallography, binding studies and molecular dynamics.
Masternak M, Koch A, Laulumaa S, Tapken D, Hollmann M, Jørgensen FS, Kastrup JS
FEBS J (2022)
PMID: 36128700

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178950 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate receptor ionotropic, delta-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 266 amino acids
Theoretical weight: 29.69 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q62640 (Residues: 436-547, 664-814; Coverage: 27%)
Gene name: Grid1
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 5 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX IV BEAMLINE BioMAX
Spacegroup: P21
Unit cell:
a: 33.31Å b: 136.44Å c: 54.61Å
α: 90° β: 96.98° γ: 90°
R-values:
R R work R free
0.217 0.215 0.252
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

GluD receptors are functional ion channels.
Kumar et al. (2023)