› 7z5k

X-ray diffraction
2.28Å resolution

Transcription factor MYF5 bound to non-symmetrical site

Released:
DOI: 10.2210/pdb7z5k/pdb
PDB entry 7z5k coloured by chain, front view.
PDB entry 7z5k coloured by chain, side view.
PDB entry 7z5k coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Morgunova E, Popov A, Yin Y, Taipale J

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-270276 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):
Myogenic factor 5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 57 amino acids
Theoretical weight: 6.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P13349 (Residues: 82-137; Coverage: 22%)
Gene names: BHLHC2, MYF5
Sequence domains: Helix-loop-helix DNA-binding domain
DNA (5'-D(P*GP*CP*GP*CP*AP*AP*CP*AP*GP*CP*TP*GP*AP*CP*GP*CP*GP*T)-3') Chain: E
Molecule details ›
Chain: E
Length: 18 nucleotides
Theoretical weight: 5.53 KDa
Source organism: Homo sapiens
Expression system: Not provided
DNA (5'-D(P*AP*CP*GP*CP*GP*TP*CP*AP*GP*CP*TP*GP*TP*TP*GP*CP*GP*C)-3') Chain: F
Molecule details ›
Chain: F
Length: 18 nucleotides
Theoretical weight: 5.51 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2
Unit cell:
a: 170.443Å b: 33.839Å c: 53.541Å
α: 90° β: 91.88° γ: 90°
R-values:
R R work R free
0.231 0.229 0.266
Expression systems:
  • Escherichia coli
  • Not provided

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