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7z77 Overview
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![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>7z77</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Elongin-B</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Elongin-C</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>von Hippel-Lindau disease tumor suppressor</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Probable global transcription activator SNF2L2</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(2~{S},4~{R})-~{N}-[(1~{S})-4-[4-(4-bromanyl-7-cyclopentyl-5-oxidanylidene-benzimidazolo[1,2-a]quinazolin-9-yl)piperidin-1-yl]-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]butyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7z77_deposited_chain_front_image-800x800.png "PDB entry 7z77 coloured by chain, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>7z77</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Elongin-B</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Elongin-C</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>von Hippel-Lindau disease tumor suppressor</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Probable global transcription activator SNF2L2</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(2~{S},4~{R})-~{N}-[(1~{S})-4-[4-(4-bromanyl-7-cyclopentyl-5-oxidanylidene-benzimidazolo[1,2-a]quinazolin-9-yl)piperidin-1-yl]-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]butyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7z77_deposited_chain_side_image-800x800.png "PDB entry 7z77 coloured by chain, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>7z77</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Elongin-B</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Elongin-C</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>von Hippel-Lindau disease tumor suppressor</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Probable global transcription activator SNF2L2</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(2~{S},4~{R})-~{N}-[(1~{S})-4-[4-(4-bromanyl-7-cyclopentyl-5-oxidanylidene-benzimidazolo[1,2-a]quinazolin-9-yl)piperidin-1-yl]-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]butyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7z77_deposited_chain_top_image-800x800.png "PDB entry 7z77 coloured by chain, top view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>7z77</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Elongin-B</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Elongin-C</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>von Hippel-Lindau disease tumor suppressor</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Probable global transcription activator SNF2L2</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(2~{S},4~{R})-~{N}-[(1~{S})-4-[4-(4-bromanyl-7-cyclopentyl-5-oxidanylidene-benzimidazolo[1,2-a]quinazolin-9-yl)piperidin-1-yl]-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]butyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7z77_deposited_chemically_distinct_molecules_front_image-800x800.png "PDB entry 7z77 coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>7z77</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Elongin-B</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Elongin-C</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>von Hippel-Lindau disease tumor suppressor</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Probable global transcription activator SNF2L2</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(2~{S},4~{R})-~{N}-[(1~{S})-4-[4-(4-bromanyl-7-cyclopentyl-5-oxidanylidene-benzimidazolo[1,2-a]quinazolin-9-yl)piperidin-1-yl]-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]butyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7z77_deposited_chemically_distinct_molecules_side_image-800x800.png "PDB entry 7z77 coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>7z77</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Elongin-B</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Elongin-C</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>von Hippel-Lindau disease tumor suppressor</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Probable global transcription activator SNF2L2</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(2~{S},4~{R})-~{N}-[(1~{S})-4-[4-(4-bromanyl-7-cyclopentyl-5-oxidanylidene-benzimidazolo[1,2-a]quinazolin-9-yl)piperidin-1-yl]-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]butyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7z77_deposited_chemically_distinct_molecules_top_image-800x800.png "PDB entry 7z77 coloured by chemically distinct molecules, top view.")
![<div class='caption-body'>Hetero tetrameric assembly 1 of PDB entry <span class='highlight'>7z77</span> contains 1 copy of <span class='highlight'>(2~{S},4~{R})-~{N}-[(1~{S})-4-[4-(4-bromanyl-7-cyclopentyl-5-oxidanylidene-benzimidazolo[1,2-a]quinazolin-9-yl)piperidin-1-yl]-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]butyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide</span>. Front view.</div>](https://www.ebi.ac.uk/pdbe/static/entry/7z77_entity_5_front_image-800x800.png "(2~{S},4~{R})-~{N}-[(1~{S})-4-[4-(4-bromanyl-7-cyclopentyl-5-oxidanylidene-benzimidazolo[1,2-a]quinazolin-9-yl)piperidin-1-yl]-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]butyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide in PDB entry 7z77, assembly 1, front view.")
![<div class='caption-body'>Hetero tetrameric assembly 1 of PDB entry <span class='highlight'>7z77</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Elongin-B</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Elongin-C</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>von Hippel-Lindau disease tumor suppressor</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Probable global transcription activator SNF2L2</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(2~{S},4~{R})-~{N}-[(1~{S})-4-[4-(4-bromanyl-7-cyclopentyl-5-oxidanylidene-benzimidazolo[1,2-a]quinazolin-9-yl)piperidin-1-yl]-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]butyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7z77_assembly_1_chemically_distinct_molecules_front_image-800x800.png "Hetero tetrameric assembly 1 of PDB entry 7z77 coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>Hetero tetrameric assembly 1 of PDB entry <span class='highlight'>7z77</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Elongin-B</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Elongin-C</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>von Hippel-Lindau disease tumor suppressor</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Probable global transcription activator SNF2L2</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(2~{S},4~{R})-~{N}-[(1~{S})-4-[4-(4-bromanyl-7-cyclopentyl-5-oxidanylidene-benzimidazolo[1,2-a]quinazolin-9-yl)piperidin-1-yl]-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]butyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7z77_assembly_1_chemically_distinct_molecules_side_image-800x800.png "Hetero tetrameric assembly 1 of PDB entry 7z77 coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>Hetero tetrameric assembly 1 of PDB entry <span class='highlight'>7z77</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Elongin-B</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Elongin-C</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>von Hippel-Lindau disease tumor suppressor</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Probable global transcription activator SNF2L2</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(2~{S},4~{R})-~{N}-[(1~{S})-4-[4-(4-bromanyl-7-cyclopentyl-5-oxidanylidene-benzimidazolo[1,2-a]quinazolin-9-yl)piperidin-1-yl]-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]butyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/7z77_assembly_1_chemically_distinct_molecules_top_image-800x800.png "Hetero tetrameric assembly 1 of PDB entry 7z77 coloured by chemically distinct molecules, top view.")