› 7z8a

X-ray diffraction
2.06Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170491 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
KH domain-containing, RNA-binding, signal transduction-associated protein 1 Chain: AAA
Molecule details ›
Chain: AAA
Length: 115 amino acids
Theoretical weight: 13.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07666 (Residues: 145-259; Coverage: 26%)
Gene names: KHDRBS1, SAM68
Sequence domains: KH domain

Ligands and Environments

4 bound ligands:
Ligand NO3 8 x NO3
Ligand LI 1 x LI
Ligand EDO 5 x EDO
Ligand PGO 3 x PGO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: P4122
Unit cell:
a: 68.565Å b: 68.565Å c: 83.195Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.204 0.246
Expression system: Escherichia coli

Quick links

Citations

1 citations in other articles

Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts.
Nadal et al. (2023)