7z9r

Electron Microscopy
4.2Å resolution

CRYO-EM STRUCTURE OF SARS-COV-2 SPIKE : H11-H4 Q98R H100E nanobody complex in 2Up1Down conformation

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-225156 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Fibritin; Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1260 amino acids
Theoretical weight: 139.88 KDa
Source organisms: Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-1208; Coverage: 95%)
  • Canonical: P10104 (Residues: 458-485; Coverage: 6%)
Gene names: 2, S, wac
Sequence domains:
Nanobody H11-H4 Q98R H100E Chains: X, Y, Z
Molecule details ›
Chains: X, Y, Z
Length: 127 amino acids
Theoretical weight: 14.11 KDa
Source organism: Lama glama
Expression system: Escherichia coli

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.2Å
Relevant EMDB volumes: EMD-14576
Expression systems:
  • Homo sapiens
  • Escherichia coli