› 7zam

X-ray diffraction
2.79Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170491 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
KH domain-containing, RNA-binding, signal transduction-associated protein 1 Chains: AAA, BBB
Molecule details ›
Chains: AAA, BBB
Length: 118 amino acids
Theoretical weight: 13.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07666 (Residues: 143-260; Coverage: 27%)
Gene names: KHDRBS1, SAM68
Sequence domains: KH domain

Ligands and Environments

4 bound ligands:
Ligand IOD 2 x IOD
Ligand EDO 15 x EDO
Ligand GOL 1 x GOL
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: C2221
Unit cell:
a: 138.459Å b: 138.701Å c: 82.337Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.186 0.214
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts.
Nadal et al. (2023)
2 more