Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Interleukin-17, chordata
- Cystine-knot cytokine
- Interleukin-17 receptor-like
- Interleukin-17 family
- Interleukin-17 receptor C/E, N-terminal
- Interleukin-17 receptor A/B, FnIII-like domain 2 superfamily
- Interleukin-17 receptor, fibronectin-III-like domain 1
- Interleukin-17 receptor A/B, FnIII-like domain 1 superfamily
Structure analysis Details
Assembly composition:
hetero octamer (preferred)
PDBe Complex ID:
PDB-CPX-172506 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Interleukin-17A
Molecule details ›
Chains: A, B
Length: 123 amino acids
Theoretical weight: 14.18 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Interleukin-17
Length: 123 amino acids
Theoretical weight: 14.18 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q16552 (Residues: 34-155; Coverage: 92%)
Sequence domains: Interleukin-17
Interleukin-17 receptor A
Molecule details ›
Chain: C
Length: 292 amino acids
Theoretical weight: 34.07 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 292 amino acids
Theoretical weight: 34.07 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: Q96F46 (Residues: 33-320; Coverage: 35%)
Sequence domains:
Interleukin-17 receptor C
Molecule details ›
Chain: D
Length: 453 amino acids
Theoretical weight: 50.56 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Interleukin-17 receptor extracellular region
Length: 453 amino acids
Theoretical weight: 50.56 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: Q8NAC3 (Residues: 95-538; Coverage: 58%)
Sequence domains: Interleukin-17 receptor extracellular region
