7zjv

X-ray diffraction
2.4Å resolution

Structure of human USPL1 in covalent complex with DeltaN-SUMO2/3-PA probe

Released:
Model geometry
Fit model/data

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-274062 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
SUMO-specific isopeptidase USPL1 Chain: A
Molecule details ›
Chain: A
Length: 287 amino acids
Theoretical weight: 33.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5W0Q7 (Residues: 218-502; Coverage: 26%)
Gene names: C13orf22, D13S106, USPL1
Sequence domains: Ubiquitin-specific peptidase-like, SUMO isopeptidase
Small ubiquitin-related modifier 2 Chain: B
Molecule details ›
Chain: B
Length: 76 amino acids
Theoretical weight: 8.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61956 (Residues: 18-92; Coverage: 79%)
Gene names: SMT3B, SMT3H2, SUMO2
Sequence domains: Ubiquitin-2 like Rad60 SUMO-like

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P41212
Unit cell:
a: 95.708Å b: 95.708Å c: 82.88Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.232 0.23 0.258
Expression system: Escherichia coli