› 7zjw

Electron Microscopy
2.8Å resolution

Rabbit 80S ribosome as it decodes the Sec-UGA codon

Released:
DOI: 10.2210/pdb7zjw/pdb
PDB entry 7zjw coloured by chain, front view.
PDB entry 7zjw coloured by chain, side view.
PDB entry 7zjw coloured by chain, top view.
Source organisms:
Primary publication:
Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.
Hilal T, Killam BY, Grozdanović M, Dobosz-Bartoszek M, Loerke J, Bürger J, Mielke T, Copeland PR, Simonović M, Spahn CMT
Science 376 1338-1343 (2022)
PMID: 35709277
Related structures: EMD-14751

Function and Biology Details

Reaction catalysed: 
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 86-mer (preferred)
PDBe Complex ID:
PDB-CPX-249407 (preferred)
Entry contents:
79 distinct polypeptide molecules
7 distinct RNA molecules
Macromolecules (86 distinct):
Selenocysteine-specific elongation factor Chain: E
Molecule details ›
Chain: E
Length: 616 amino acids
Theoretical weight: 67.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P57772 (Residues: 1-596; Coverage: 100%)
Gene names: EEFSEC, SELB
Sequence domains:
Selenocysteine insertion sequence-binding protein 2 Chain: B
Molecule details ›
Chain: B
Length: 854 amino acids
Theoretical weight: 95.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96T21 (Residues: 1-854; Coverage: 100%)
Gene names: SBP2, SECISBP2
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Large ribosomal subunit protein uL2 Chain: LD
Molecule details ›
Chain: LD
Length: 257 amino acids
Theoretical weight: 28.09 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A8B8VPA8 (Residues: 1-257; Coverage: 100%)
Gene name: RPL8
Sequence domains:
Large ribosomal subunit protein uL3 Chain: LE
Molecule details ›
Chain: LE
Length: 403 amino acids
Theoretical weight: 46.12 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TL06 (Residues: 1-403; Coverage: 100%)
Gene name: RPL3
Sequence domains: Ribosomal protein L3
Large ribosomal subunit protein uL4 Chain: LF
Molecule details ›
Chain: LF
Length: 413 amino acids
Theoretical weight: 46.43 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SVW5 (Residues: 1-413; Coverage: 100%)
Gene name: RPL4
Sequence domains:
Large ribosomal subunit protein uL18 Chain: LG
Molecule details ›
Chain: LG
Length: 297 amino acids
Theoretical weight: 34.52 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P19949 (Residues: 1-297; Coverage: 100%)
Gene name: RPL5
Large ribosomal subunit protein eL6 Chain: LH
Molecule details ›
Chain: LH
Length: 291 amino acids
Theoretical weight: 33.03 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SKF7 (Residues: 1-291; Coverage: 100%)
Gene name: RPL6
Sequence domains:
Large ribosomal subunit protein uL30 Chain: LI
Molecule details ›
Chain: LI
Length: 247 amino acids
Theoretical weight: 29.2 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A7J8C453 (Residues: 12-258; Coverage: 96%)
Gene name: HJG63_016928
Sequence domains:
Large ribosomal subunit protein eL8 Chain: LJ
Molecule details ›
Chain: LJ
Length: 266 amino acids
Theoretical weight: 30.06 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P62424 (Residues: 1-266; Coverage: 100%)
Gene names: RPL7A, SURF-3, SURF3
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Large ribosomal subunit protein uL6 Chain: LK
Molecule details ›
Chain: LK
Length: 192 amino acids
Theoretical weight: 21.87 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SWI6 (Residues: 1-192; Coverage: 100%)
Gene name: RPL9
Sequence domains: Ribosomal protein L6
Large ribosomal subunit protein uL16 Chain: LL
Molecule details ›
Chain: LL
Length: 214 amino acids
Theoretical weight: 24.64 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: B7NZQ2 (Residues: 1-214; Coverage: 100%)
Gene name: RPL10
Sequence domains: Ribosomal protein L16p/L10e
Large ribosomal subunit protein uL5 Chain: LM
Molecule details ›
Chain: LM
Length: 178 amino acids
Theoretical weight: 20.29 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TUB8 (Residues: 1-178; Coverage: 100%)
Gene name: RPL11
Sequence domains:
Large ribosomal subunit protein eL13 Chain: LO
Molecule details ›
Chain: LO
Length: 211 amino acids
Theoretical weight: 24.33 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TKB3 (Residues: 1-211; Coverage: 100%)
Gene name: RPL13
Sequence domains: Ribosomal protein L13e
Large ribosomal subunit protein eL14 Chain: LP
Molecule details ›
Chain: LP
Length: 218 amino acids
Theoretical weight: 23.87 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SZ12 (Residues: 1-218; Coverage: 100%)
Gene name: RPL14
Sequence domains: Ribosomal protein L14
Large ribosomal subunit protein eL15 Chain: LQ
Molecule details ›
Chain: LQ
Length: 204 amino acids
Theoretical weight: 24.21 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1T0C1 (Residues: 1-204; Coverage: 100%)
Gene name: RPL15
Sequence domains: Ribosomal L15
Large ribosomal subunit protein uL13 Chain: LR
Molecule details ›
Chain: LR
Length: 203 amino acids
Theoretical weight: 23.53 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A0N8ETI8 (Residues: 1-203; Coverage: 100%)
Gene name: RPL13A
Sequence domains: Ribosomal protein L13
Large ribosomal subunit protein uL22 Chain: LS
Molecule details ›
Chain: LS
Length: 184 amino acids
Theoretical weight: 21.44 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A8J4KQ25 (Residues: 1-184; Coverage: 100%)
Gene names: FQV12_0008225, Rpl17
Sequence domains: Ribosomal protein L22p/L17e
Large ribosomal subunit protein uL15/eL18 domain-containing protein Chain: LT
Molecule details ›
Chain: LT
Length: 188 amino acids
Theoretical weight: 21.7 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: F6QKI9 (Residues: 1-188; Coverage: 100%)
Gene name: RPL18
Sequence domains: Ribosomal protein 60S L18 and 50S L18e
Ribosomal protein L19 Chain: LU
Molecule details ›
Chain: LU
Length: 196 amino acids
Theoretical weight: 23.54 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A2J8KH59 (Residues: 1-196; Coverage: 100%)
Gene name: CK820_G0039174
Sequence domains: Ribosomal protein L19e
Large ribosomal subunit protein eL20 Chain: LV
Molecule details ›
Chain: LV
Length: 176 amino acids
Theoretical weight: 20.75 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A1Z5LHJ5 (Residues: 1-176; Coverage: 100%)
Sequence domains: Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
Large ribosomal subunit protein eL21 Chain: LW
Molecule details ›
Chain: LW
Length: 160 amino acids
Theoretical weight: 18.61 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SHQ2 (Residues: 1-160; Coverage: 100%)
Gene name: RPL21
Sequence domains: Ribosomal protein L21e
Large ribosomal subunit protein eL22 Chain: LX
Molecule details ›
Chain: LX
Length: 128 amino acids
Theoretical weight: 14.76 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: Q4R5I3 (Residues: 1-128; Coverage: 100%)
Gene names: QflA-13079, RPL22
Sequence domains: Ribosomal L22e protein family
Large ribosomal subunit protein uL14 Chain: LY
Molecule details ›
Chain: LY
Length: 140 amino acids
Theoretical weight: 14.89 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A3P9HH38 (Residues: 1-140; Coverage: 100%)
Sequence domains: Ribosomal protein L14p/L23e
Large ribosomal subunit protein eL24 Chain: LZ
Molecule details ›
Chain: LZ
Length: 157 amino acids
Theoretical weight: 17.83 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SE28 (Residues: 1-157; Coverage: 100%)
Gene name: RPL24
Sequence domains: Ribosomal protein L24e
Large ribosomal subunit protein uL23 Chain: La
Molecule details ›
Chain: La
Length: 156 amino acids
Theoretical weight: 17.77 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SE76 (Residues: 1-156; Coverage: 100%)
Gene name: RPL23A
Sequence domains:
Large ribosomal subunit protein uL24 Chain: Lb
Molecule details ›
Chain: Lb
Length: 145 amino acids
Theoretical weight: 17.3 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A5N3X333 (Residues: 1-145; Coverage: 100%)
Gene name: FD755_020861
Sequence domains:
60S ribosomal protein L27 Chain: Lc
Molecule details ›
Chain: Lc
Length: 136 amino acids
Theoretical weight: 15.84 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A851LWS6 (Residues: 1-136; Coverage: 100%)
Gene names: CORCRI_R11721, Rpl27
Sequence domains:
Large ribosomal subunit protein uL15 Chain: Ld
Molecule details ›
Chain: Ld
Length: 148 amino acids
Theoretical weight: 16.62 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SNY0 (Residues: 1-148; Coverage: 100%)
Gene name: RPL27A
Sequence domains: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
Large ribosomal subunit protein eL29 Chain: Le
Molecule details ›
Chain: Le
Length: 245 amino acids
Theoretical weight: 26.72 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SGR6 (Residues: 1-245; Coverage: 100%)
Gene name: RPL29
Sequence domains: Ribosomal L29e protein family
Large ribosomal subunit protein eL30 Chain: Lf
Molecule details ›
Chain: Lf
Length: 115 amino acids
Theoretical weight: 12.81 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TDL2 (Residues: 1-115; Coverage: 100%)
Gene name: RPL30
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Large ribosomal subunit protein eL31 Chain: Lg
Molecule details ›
Chain: Lg
Length: 125 amino acids
Theoretical weight: 14.49 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SHG0 (Residues: 1-125; Coverage: 100%)
Gene name: RPL31
Sequence domains: Ribosomal protein L31e
Large ribosomal subunit protein eL32 Chain: Lh
Molecule details ›
Chain: Lh
Length: 135 amino acids
Theoretical weight: 15.9 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TUN8 (Residues: 1-135; Coverage: 100%)
Gene name: RPL32
Sequence domains: Ribosomal protein L32
Large ribosomal subunit protein eL33 Chain: Li
Molecule details ›
Chain: Li
Length: 110 amino acids
Theoretical weight: 12.58 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SF08 (Residues: 1-110; Coverage: 100%)
Gene name: RPL35A
Sequence domains: Ribosomal protein L35Ae
Large ribosomal subunit protein eL34 Chain: Lj
Molecule details ›
Chain: Lj
Length: 117 amino acids
Theoretical weight: 13.33 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TXG5 (Residues: 1-117; Coverage: 100%)
Gene name: RPL34
Sequence domains: Ribosomal protein L34e
Large ribosomal subunit protein uL29 Chain: Lk
Molecule details ›
Chain: Lk
Length: 123 amino acids
Theoretical weight: 14.57 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SIT5 (Residues: 1-123; Coverage: 100%)
Gene name: RPL35
Sequence domains: Ribosomal L29 protein
60S ribosomal protein L36 Chain: Ll
Molecule details ›
Chain: Ll
Length: 105 amino acids
Theoretical weight: 12.26 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A1S3FQR5 (Residues: 1-105; Coverage: 100%)
Gene name: Rpl36
Sequence domains: Ribosomal protein L36e
Large ribosomal subunit protein eL37 Chain: Lm
Molecule details ›
Chain: Lm
Length: 97 amino acids
Theoretical weight: 11.11 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: U3KPD5 (Residues: 1-97; Coverage: 100%)
Gene name: RPL37
Sequence domains: Ribosomal protein L37e
Large ribosomal subunit protein eL38 Chain: Ln
Molecule details ›
Chain: Ln
Length: 70 amino acids
Theoretical weight: 8.24 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A1A7W9T9 (Residues: 1-70; Coverage: 100%)
Gene name: RPL38
Sequence domains: Ribosomal L38e protein family
Large ribosomal subunit protein eL39 Chain: Lo
Molecule details ›
Chain: Lo
Length: 51 amino acids
Theoretical weight: 6.46 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TTN1 (Residues: 1-51; Coverage: 100%)
Sequence domains: Ribosomal L39 protein
Ubiquitin-ribosomal protein eL40 fusion protein Chain: Lp
Molecule details ›
Chain: Lp
Length: 128 amino acids
Theoretical weight: 14.8 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A8C8Y9V5 (Residues: 1-128; Coverage: 100%)
Gene name: UBA52
Sequence domains:
Large ribosomal subunit protein eL42 Chain: Lq
Molecule details ›
Chain: Lq
Length: 106 amino acids
Theoretical weight: 12.49 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A7J7V6K8 (Residues: 33-138; Coverage: 77%)
Gene name: mPipKuh1_015125
Sequence domains: Ribosomal protein L44
60S ribosomal protein L37a Chain: Lr
Molecule details ›
Chain: Lr
Length: 92 amino acids
Theoretical weight: 10.3 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A6I9ZMF9 (Residues: 1-92; Coverage: 100%)
Gene name: RPL37A
Sequence domains: Ribosomal L37ae protein family
Large ribosomal subunit protein eL28 Chain: Ls
Molecule details ›
Chain: Ls
Length: 137 amino acids
Theoretical weight: 15.84 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A4U1EJN3 (Residues: 56-192; Coverage: 71%)
Gene name: EI555_020534
Sequence domains: Ribosomal L28e protein family
Large ribosomal subunit protein uL10 Chain: Lt
Molecule details ›
Chain: Lt
Length: 318 amino acids
Theoretical weight: 34.36 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SPK4 (Residues: 1-318; Coverage: 100%)
Gene name: RPLP0
Sequence domains:
Large ribosomal subunit protein uL1 Chain: Lx
Molecule details ›
Chain: Lx
Length: 217 amino acids
Theoretical weight: 24.88 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SKZ8 (Residues: 1-217; Coverage: 100%)
Gene name: RPL10A
Sequence domains: Ribosomal protein L1p/L10e family
40S ribosomal protein S27 Chain: SB
Molecule details ›
Chain: SB
Length: 84 amino acids
Theoretical weight: 9.48 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A7J8BG50 (Residues: 1-84; Coverage: 100%)
Gene name: HJG63_016964
Sequence domains: Ribosomal protein S27
Small ribosomal subunit protein eS28 Chain: SC
Molecule details ›
Chain: SC
Length: 69 amino acids
Theoretical weight: 7.86 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A3M0JHZ8 (Residues: 1-69; Coverage: 100%)
Gene name: DUI87_22462
Sequence domains: Ribosomal protein S28e
Ubiquitin-ribosomal protein eS31 fusion protein Chain: SD
Molecule details ›
Chain: SD
Length: 156 amino acids
Theoretical weight: 18 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A8C0T835 (Residues: 1-156; Coverage: 100%)
Gene name: RPS27A
Sequence domains:
Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Chain: SE
Molecule details ›
Chain: SE
Length: 133 amino acids
Theoretical weight: 14.5 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1T8A2 (Residues: 1-133; Coverage: 100%)
Gene name: FAU
Sequence domains:
40S ribosomal protein S26 Chain: SF
Molecule details ›
Chain: SF
Length: 115 amino acids
Theoretical weight: 13.05 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A2K5LQY6 (Residues: 1-115; Coverage: 100%)
Sequence domains: Ribosomal protein S26e
Small ribosomal subunit protein RACK1 Chain: SG
Molecule details ›
Chain: SG
Length: 317 amino acids
Theoretical weight: 35.12 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A2K6K8B0 (Residues: 1-317; Coverage: 100%)
Gene name: RACK1
Sequence domains: WD domain, G-beta repeat
Small ribosomal subunit protein uS14 Chain: SH
Molecule details ›
Chain: SH
Length: 56 amino acids
Theoretical weight: 6.69 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1U7M4 (Residues: 1-56; Coverage: 100%)
Gene name: RPS29
Sequence domains: Ribosomal protein S14p/S29e
Small ribosomal subunit protein uS2 Chain: SL
Molecule details ›
Chain: SL
Length: 295 amino acids
Theoretical weight: 32.97 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TLT8 (Residues: 1-295; Coverage: 100%)
Gene name: RPSA
Sequence domains:
Small ribosomal subunit protein eS1 Chain: SM
Molecule details ›
Chain: SM
Length: 264 amino acids
Theoretical weight: 30 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SS70 (Residues: 1-264; Coverage: 100%)
Gene name: RPS3A
Sequence domains: Ribosomal S3Ae family
Small ribosomal subunit protein uS5 Chain: SN
Molecule details ›
Chain: SN
Length: 293 amino acids
Theoretical weight: 31.29 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: O18789 (Residues: 1-293; Coverage: 100%)
Gene name: RPS2
Sequence domains:
Small ribosomal subunit protein uS3 Chain: SO
Molecule details ›
Chain: SO
Length: 281 amino acids
Theoretical weight: 31.15 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TNM3 (Residues: 1-243; Coverage: 100%)
Gene name: RPS3
Sequence domains:
Small ribosomal subunit protein eS4 Chain: SP
Molecule details ›
Chain: SP
Length: 263 amino acids
Theoretical weight: 29.65 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: Q76N24 (Residues: 1-263; Coverage: 100%)
Gene name: RPS4X
Sequence domains:
Small ribosomal subunit protein uS7 Chain: SQ
Molecule details ›
Chain: SQ
Length: 204 amino acids
Theoretical weight: 22.91 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A5F9DBR8 (Residues: 9-212; Coverage: 96%)
Gene name: RPS5
Sequence domains: Ribosomal protein S7p/S5e
Small ribosomal subunit protein eS6 Chain: SR
Molecule details ›
Chain: SR
Length: 249 amino acids
Theoretical weight: 28.75 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P62753 (Residues: 1-249; Coverage: 100%)
Gene names: OK/SW-cl.2, RPS6
Sequence domains: Ribosomal protein S6e
Small ribosomal subunit protein eS7 Chain: SS
Molecule details ›
Chain: SS
Length: 432 amino acids
Theoretical weight: 47.36 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SVB0 (Residues: 1-194; Coverage: 100%)
Gene name: RPS7
Small ribosomal subunit protein eS8 Chain: ST
Molecule details ›
Chain: ST
Length: 208 amino acids
Theoretical weight: 24.26 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: Q5E958 (Residues: 1-208; Coverage: 100%)
Gene name: RPS8
Sequence domains: Ribosomal protein S8e
Small ribosomal subunit protein uS4 Chain: SU
Molecule details ›
Chain: SU
Length: 194 amino acids
Theoretical weight: 22.64 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: B7NZS8 (Residues: 1-194; Coverage: 100%)
Gene name: RPS9
Sequence domains:
Small ribosomal subunit protein eS10 Chain: SV
Molecule details ›
Chain: SV
Length: 165 amino acids
Theoretical weight: 18.93 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TPV3 (Residues: 1-165; Coverage: 100%)
Sequence domains: Plectin/S10 domain
Small ribosomal subunit protein uS17 Chain: SW
Molecule details ›
Chain: SW
Length: 158 amino acids
Theoretical weight: 18.47 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TRM4 (Residues: 1-158; Coverage: 100%)
Gene name: RPS11
Sequence domains:
Small ribosomal subunit protein eS12 Chain: SX
Molecule details ›
Chain: SX
Length: 132 amino acids
Theoretical weight: 14.54 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SFR8 (Residues: 1-132; Coverage: 100%)
Gene name: RPS12
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Small ribosomal subunit protein uS15 Chain: SY
Molecule details ›
Chain: SY
Length: 151 amino acids
Theoretical weight: 17.26 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A663F1C0 (Residues: 1-151; Coverage: 100%)
Gene name: RPS13
Sequence domains:
Small ribosomal subunit protein uS11 Chain: SZ
Molecule details ›
Chain: SZ
Length: 151 amino acids
Theoretical weight: 16.3 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A7L0BEC6 (Residues: 1-151; Coverage: 100%)
Gene names: Rps14, SPITYR_R00187
Sequence domains: Ribosomal protein S11
Small ribosomal subunit protein uS19 Chain: Sa
Molecule details ›
Chain: Sa
Length: 145 amino acids
Theoretical weight: 17.05 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1U0Q2 (Residues: 1-145; Coverage: 100%)
Gene name: RPS15
Sequence domains: Ribosomal protein S19
Small ribosomal subunit protein uS9 Chain: Sb
Molecule details ›
Chain: Sb
Length: 172 amino acids
Theoretical weight: 19.21 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SGX4 (Residues: 1-146; Coverage: 100%)
Gene name: RPS16
Sequence domains: Ribosomal protein S9/S16
Small ribosomal subunit protein eS17 Chain: Sc
Molecule details ›
Chain: Sc
Length: 135 amino acids
Theoretical weight: 15.55 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TU13 (Residues: 1-135; Coverage: 100%)
Gene name: RPS17
Sequence domains: Ribosomal S17
Small ribosomal subunit protein uS13 Chain: Sd
Molecule details ›
Chain: Sd
Length: 152 amino acids
Theoretical weight: 17.8 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: H0WTR0 (Residues: 1-152; Coverage: 100%)
Gene name: RPS18
Sequence domains: Ribosomal protein S13/S18
Small ribosomal subunit protein eS19 Chain: Se
Molecule details ›
Chain: Se
Length: 145 amino acids
Theoretical weight: 16.1 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A2Y9E7Q1 (Residues: 1-145; Coverage: 100%)
Gene name: RPS19
Sequence domains: Ribosomal protein S19e
Small ribosomal subunit protein uS10 Chain: Sf
Molecule details ›
Chain: Sf
Length: 119 amino acids
Theoretical weight: 13.4 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SIZ2 (Residues: 1-119; Coverage: 100%)
Gene name: RPS20
Sequence domains: Ribosomal protein S10p/S20e
Small ribosomal subunit protein eS21 Chain: Sg
Molecule details ›
Chain: Sg
Length: 83 amino acids
Theoretical weight: 9.18 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A1Z5KTU7 (Residues: 1-83; Coverage: 100%)
Sequence domains: Ribosomal protein S21e
Small ribosomal subunit protein uS8 Chain: Sh
Molecule details ›
Chain: Sh
Length: 130 amino acids
Theoretical weight: 14.87 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TG89 (Residues: 1-130; Coverage: 100%)
Gene name: RPS15A
Sequence domains: Ribosomal protein S8
Small ribosomal subunit protein uS12 Chain: Si
Molecule details ›
Chain: Si
Length: 143 amino acids
Theoretical weight: 15.86 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SZ47 (Residues: 1-143; Coverage: 100%)
Gene name: RPS23
Sequence domains: Ribosomal protein S12/S23
40S ribosomal protein S24 Chain: Sj
Molecule details ›
Chain: Sj
Length: 130 amino acids
Theoretical weight: 15.11 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A6J1UT65 (Residues: 1-130; Coverage: 100%)
Gene name: RPS24
Sequence domains: Ribosomal protein S24e
40S ribosomal protein S25 Chain: Sk
Molecule details ›
Chain: Sk
Length: 124 amino acids
Theoretical weight: 13.65 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A2U4BVW1 (Residues: 2-125; Coverage: 99%)
Gene name: RPS25
Sequence domains: S25 ribosomal protein
Small ribosomal subunit protein eS32 Chain: Sl
Molecule details ›
Chain: Sl
Length: 25 amino acids
Theoretical weight: 3.47 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A087WNH4 (Residues: 1-25; Coverage: 100%)
Gene name: RPL41
Sequence domains: Ribosomal protein L41
human Ser-tRNA-Sec Chain: F
Molecule details ›
Chain: F
Length: 90 nucleotides
Theoretical weight: 28.91 KDa
Sequence domains: Selenocysteine transfer RNA
CrPV IRES Chain: I
Molecule details ›
Chain: I
Length: 1072 nucleotides
Theoretical weight: 345.55 KDa
Sequence domains: Cripavirus internal ribosome entry site (IRES)
GPX4 SECIS element Chain: S
Molecule details ›
Chain: S
Length: 855 nucleotides
Theoretical weight: 275.72 KDa
Sequence domains: Selenocysteine insertion sequence 1
28S ribosomal RNA Chain: L5
Molecule details ›
Chain: L5
Length: 4808 nucleotides
Theoretical weight: 1557.51 KDa
Sequence domains: Eukaryotic large subunit ribosomal RNA
5S ribosomal RNA Chain: L7
Molecule details ›
Chain: L7
Length: 119 nucleotides
Theoretical weight: 38.35 KDa
Sequence domains: 5S ribosomal RNA
5.8S ribosomal RNA Chain: L8
Molecule details ›
Chain: L8
Length: 158 nucleotides
Theoretical weight: 50.81 KDa
Sequence domains: 5.8S ribosomal RNA
18S Ribosomal RNA Chain: S2
Molecule details ›
Chain: S2
Length: 1870 nucleotides
Theoretical weight: 603.81 KDa
Sequence domains: Eukaryotic small subunit ribosomal RNA

Ligands and Environments

6 bound ligands:
Ligand GTP 2 x GTP
Ligand SER 1 x SER
Ligand MG 225 x MG
Ligand K 18 x K
Ligand ZN 9 x ZN
Ligand NA 1 x NA
18 modified residues:
Ligand A2M 33 x A2M
Ligand OMG 30 x OMG
Ligand 1MA 1 x 1MA
Ligand OMC 20 x OMC
Ligand PSU 96 x PSU
Ligand OMU 17 x OMU
Ligand 5MC 2 x 5MC
Ligand 6MZ 2 x 6MZ
Ligand UR3 1 x UR3
Ligand HIC 1 x HIC
Ligand AYA 1 x AYA
Ligand MLZ 2 x MLZ
Ligand M3L 1 x M3L
Ligand SAC 3 x SAC
Ligand 7MG 1 x 7MG
Ligand MA6 2 x MA6
Ligand NMM 1 x NMM
Ligand HY3 1 x HY3

Experiments and Validation Details

Entry percentile scores
Resolution: 2.8Å
Relevant EMDB volumes: EMD-14751
Expression system: Escherichia coli

Quick links

Citations

5 review citations

The diverse structural modes of tRNA binding and recognition.
Biela et al. (2023)
4 more

1 mention without citation

A homozygous mutation in the human selenocysteine tRNA gene impairs UGA recoding activity and selenoproteome regulation by selenium.
Vindry et al. (2023)