7zme

Electron Microscopy
2.83Å resolution

CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 2) - membrane arm

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 26-mer (preferred)
PDBe Complex ID:
PDB-CPX-271190 (preferred)
Entry contents:
26 distinct polypeptide molecules
Macromolecules (26 distinct):
NADH-ubiquinone oxidoreductase chain 1 Chain: 1
Molecule details ›
Chain: 1
Length: 378 amino acids
Theoretical weight: 41.72 KDa
Source organism: Thermochaetoides thermophila DSM 1495
UniProt:
  • Canonical: G1DJA6 (Residues: 1-378; Coverage: 100%)
Gene name: CTHT_m000470
Sequence domains: NADH dehydrogenase
NADH-ubiquinone oxidoreductase chain 2 Chain: 2
Molecule details ›
Chain: 2
Length: 571 amino acids
Theoretical weight: 64.13 KDa
Source organism: Thermochaetoides thermophila DSM 1495
UniProt:
  • Canonical: G1DJ98 (Residues: 1-571; Coverage: 100%)
Gene name: CTHT_m000270
Sequence domains: Proton-conducting membrane transporter
NADH-ubiquinone oxidoreductase chain 3 Chain: 3
NADH-ubiquinone oxidoreductase chain 4 Chain: 4
NADH-ubiquinone oxidoreductase chain 5 Chain: 5
NADH-ubiquinone oxidoreductase chain 6 Chain: 6
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 Chain: 8
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 Chain: 9
Subunit NDUFA1 of NADH-ubiquinone oxidoreductase (Complex I) Chain: D
NADH-ubiquinone oxidoreductase-like protein Chain: J
NADH-ubiquinone oxidoreductase chain 4L Chain: L
Acyl carrier protein Chain: Q
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 Chain: R
DNA replication ATP-dependent helicase/nuclease DNA2 Chain: S
NADH-ubiquinone oxidoreductase Chain: U
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 Chain: W
NADH-ubiquinone oxidoreductase-like protein Chain: X
NADH dehydrogenase (Ubiquinone)-like protein Chain: a
Subunit NDUFC2 of NADH-ubiquinone oxidoreductase (Complex I) Chain: b
Subunit NDUFB3 of NADH-ubiquinone oxidoreductase (Complex I) Chain: c
NADH-ubiquinone oxidoreductase-like protein Chain: d
Subunit NDUFB2 of NADH-ubiquinone oxidoreductase (Complex I) Chain: e
NADH-ubiquinone oxidoreductase 9.5 kDa subunit Chain: g
Subunit NDUFB6 of NADH-ubiquinone oxidoreductase (Complex I) Chain: i
NADH-ubiquinone oxidoreductase B15 subunit Chain: j
NADH-ubiquinone oxidoreductase-like protein Chain: n

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.83Å
Relevant EMDB volumes: EMD-14796