Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
ATP + H(2)O = ADP + phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Capsid protein VP1 (preferred)
PDBe Complex ID:
PDB-CPX-216251 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein 2A
Molecule details ›
Chains: A, B, C
Length: 136 amino acids
Theoretical weight: 14.47 KDa
Source organism: Aichi virus A846/88
Expression system: Escherichia coli BL21(DE3)
UniProt:
Length: 136 amino acids
Theoretical weight: 14.47 KDa
Source organism: Aichi virus A846/88
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
O91464 (Residues: 1017-1152; Coverage: 6%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID14-4
Spacegroup:
P212121
Expression system: Escherichia coli BL21(DE3)
