7zvd

X-ray diffraction
2.46Å resolution

K89 acetylated glucose-6-phosphate dehydrogenase (G6PD) in a complex with structural NADP+

Released:
Model geometry
Fit model/data

Function and Biology Details

Reaction catalysed:
D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + NADPH
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-145820 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glucose-6-phosphate 1-dehydrogenase Chain: N
Molecule details ›
Chain: N
Length: 484 amino acids
Theoretical weight: 55.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P11413 (Residues: 28-511; Coverage: 94%)
Gene name: G6PD
Sequence domains:

Ligands and Environments


Cofactor: Ligand NAP 1 x NAP
No bound ligands
1 modified residue:

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: F222
Unit cell:
a: 60.22Å b: 172.22Å c: 216.48Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.208 0.289
Expression system: Escherichia coli