› 8crr

Electron Microscopy
3Å resolution

Local refinement of Band 3-III transmembrane domains, class 1 of erythrocyte ankyrin-1 complex

Released:
DOI: 10.2210/pdb8crr/pdb
PDB entry 8crr coloured by chain, front view.
PDB entry 8crr coloured by chain, side view.
PDB entry 8crr coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Architecture of the human erythrocyte ankyrin-1 complex.
Vallese F, Kim K, Yen LY, Johnston JD, Noble AJ, Calì T, Clarke OB
Nat Struct Mol Biol 29 706-718 (2022)
PMID: 35835865
Related structures: EMD-26956

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-526853 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Glycophorin-A Chains: B, D
Molecule details ›
Chains: B, D
Length: 150 amino acids
Theoretical weight: 16.35 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02724 (Residues: 1-150; Coverage: 100%)
Gene names: GPA, GYPA, MNS
Sequence domains: Glycophorin A
Band 3 anion transport protein Chains: C, E
Molecule details ›
Chains: C, E
Length: 911 amino acids
Theoretical weight: 101.88 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02730 (Residues: 1-911; Coverage: 100%)
Gene names: AE1, DI, EPB3, SLC4A1
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
2 bound ligands:
Ligand CLR 2 x CLR
Ligand PIO 2 x PIO
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3Å
Relevant EMDB volumes: EMD-26956

Quick links

Citations

4 review citations

Bridging structural and cell biology with cryo-electron microscopy.
Nogales et al. (2024)
3 more

1 mention without citation

Architecture of the human erythrocyte ankyrin-1 complex.
Vallese et al. (2022)