› 8ct3

Electron Microscopy
3.3Å resolution

Local refinement of band3-I transmembrane region from class 2 of erythrocyte ankyrin-1 complex

Released:
DOI: 10.2210/pdb8ct3/pdb
PDB entry 8ct3 coloured by chain, front view.
PDB entry 8ct3 coloured by chain, side view.
PDB entry 8ct3 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Architecture of the human erythrocyte ankyrin-1 complex.
Vallese F, Kim K, Yen LY, Johnston JD, Noble AJ, Calì T, Clarke OB
Nat Struct Mol Biol 29 706-718 (2022)
PMID: 35835865
Related structures: EMD-26979

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136103 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Glycophorin-A Chains: B, D
Molecule details ›
Chains: B, D
Length: 150 amino acids
Theoretical weight: 16.35 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02724 (Residues: 1-150; Coverage: 100%)
Gene names: GPA, GYPA, MNS
Sequence domains: Glycophorin A
Band 3 anion transport protein Chains: C, E
Molecule details ›
Chains: C, E
Length: 911 amino acids
Theoretical weight: 101.88 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02730 (Residues: 1-911; Coverage: 100%)
Gene names: AE1, DI, EPB3, SLC4A1
Sequence domains:

Ligands and Environments

3 bound ligands:
Ligand CLR 4 x CLR
Ligand NAG 2 x NAG
Ligand PIO 2 x PIO
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.3Å
Relevant EMDB volumes: EMD-26979

Quick links

Citations

1 review citation

Alloimmune hemolytic disease of the fetus and newborn: genetics, structure, and function of the commonly involved erythrocyte antigens.
Christensen et al. (2023)
16 other articles

3 mentions without citation

Architecture of the human erythrocyte ankyrin-1 complex.
Vallese et al. (2022)
2 more