› 8dfz

Solution NMR

NMR shows why a small chemical change almost abolishes the antimicrobial activity of GccF

Released:
DOI: 10.2210/pdb8dfz/pdb
PDB entry 8dfz coloured by chain, ensemble of 10 models, front view.
PDB entry 8dfz coloured by chain, ensemble of 10 models, side view.
PDB entry 8dfz coloured by chain, ensemble of 10 models, top view.
Source organism: Lactiplantibacillus plantarum
Primary publication:
NMR Shows Why a Small Chemical Change Almost Abolishes the Antimicrobial Activity of Glycocin F.
Harjes E, Edwards PJB, Bisset SW, Patchett ML, Jameson GB, Yang SH, Navo CD, Harris PWR, Brimble MA, Norris GE
Biochemistry (2023)
PMID: 37531216

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123172 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bacteriocin glycocin F Chain: A
Molecule details ›
Chain: A
Length: 43 amino acids
Theoretical weight: 4.82 KDa
Source organism: Lactiplantibacillus plantarum
Expression system: Lactiplantibacillus plantarum
UniProt:
  • Canonical: E9K9Z1 (Residues: 22-64; Coverage: 100%)
Gene name: gccF

Ligands and Environments

1 bound ligand:
Ligand NAG 2 x NAG
1 modified residue:
Ligand EW6 1 x EW6

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: simulated annealing
Expression system: Lactiplantibacillus plantarum

Quick links

Citations

1 mention without citation

NMR Shows Why a Small Chemical Change Almost Abolishes the Antimicrobial Activity of Glycocin F.
Harjes et al. (2023)