› 8eyg

Electron Microscopy
3.73Å resolution

SARS-CoV-2 spike protein complexed with two nanobodies

Released:
DOI: 10.2210/pdb8eyg/pdb
PDB entry 8eyg coloured by chain, front view.
PDB entry 8eyg coloured by chain, side view.
PDB entry 8eyg coloured by chain, top view.
Source organisms:
Entry authors: Laughlin ZT, Patel A, Ortlund EA
Related structures: EMD-28686

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-273006 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1136 amino acids
Theoretical weight: 125.88 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 14-1149; Coverage: 90%)
Gene names: 2, S
Sequence domains:
Nanobody Chains: E, F
Molecule details ›
Chains: E, F
Length: 118 amino acids
Theoretical weight: 12.36 KDa
Source organism: Lama glama
Expression system: Lama glama

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 25 x NAG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.73Å
Relevant EMDB volumes: EMD-28686
Expression systems:
  • Homo sapiens
  • Lama glama

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