8f6x

Electron Microscopy
3.25Å resolution

cryo-EM structure of a structurally designed Human metapneumovirus F protein in complex with antibody MPE8

Released:
Entry authors: Zhou T, Kwong PD, Morano NC, Ou L
Related structures: EMD-28891

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-515310 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Fibritin; Fusion glycoprotein F0 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 522 amino acids
Theoretical weight: 56.89 KDa
Source organisms: Expression system: Homo sapiens
UniProt:
  • Canonical: G3KCK8 (Residues: 1-88, 113-485, 490-490; Coverage: 86%)
  • Canonical: P10104 (Residues: 459-484; Coverage: 5%)
Gene name: wac
Sequence domains: Fusion glycoprotein F0
MPE8 Single chain variable fragment Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 306 amino acids
Theoretical weight: 32.01 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.25Å
Relevant EMDB volumes: EMD-28891
Expression system: Homo sapiens