› 8flz

X-ray diffraction
2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111575 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Envelope glycoprotein gp160 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 358 amino acids
Theoretical weight: 39.76 KDa
Source organism: HIV-1 06TG.HT008
Expression system: Homo sapiens
UniProt:
  • Canonical: C6G099 (Residues: 39-478; Coverage: 42%)
Gene name: env
Sequence domains: Envelope glycoprotein GP120

Ligands and Environments

2 bound ligands:
Ligand NAG 26 x NAG
Ligand 7IT 4 x 7IT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P212121
Unit cell:
a: 71.082Å b: 121.925Å c: 195.931Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.264 0.263 0.283
Expression system: Homo sapiens

Quick links

Citations

2 citation in other articles

Soluble CD4 and low molecular weight CD4-mimetic compounds sensitize cells to be killed by anti-HIV cytotoxic immunoconjugates.
Pincus et al. (2023)
1 more