› 8g3u

X-ray diffraction
1.94Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-555038 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Induced myeloid leukemia cell differentiation protein Mcl-1 Chain: A
Molecule details ›
Chain: A
Length: 518 amino acids
Theoretical weight: 57.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07820 (Residues: 173-321; Coverage: 43%)
Gene names: BCL2L3, MCL1
Sequence domains: Apoptosis regulator proteins, Bcl-2 family

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC
Ligand GLC 2 x GLC
2 bound ligands:
Ligand EDO 2 x EDO
Ligand YKT 1 x YKT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21212
Unit cell:
a: 99.324Å b: 137.421Å c: 38.563Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.195 0.238
Expression system: Escherichia coli

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