8hc3

Electron Microscopy
4.35Å resolution

SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with 2 YB9-258 Fabs (2 RBD up)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero heptamer (preferred)
PDBe Complex ID:
PDB-CPX-535579 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1240 amino acids
Theoretical weight: 138.04 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 14-210, 211-211, 215-1211; Coverage: 94%)
Gene names: 2, S
Sequence domains:
Light chain of YB9-258 Chains: E, L
Molecule details ›
Chains: E, L
Length: 215 amino acids
Theoretical weight: 23.18 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Heavy chain of YB9-258 Chains: D, H
Molecule details ›
Chains: D, H
Length: 220 amino acids
Theoretical weight: 23.13 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.35Å
Relevant EMDB volumes: EMD-34650
Expression system: Homo sapiens