Function and Biology Details
Reaction catalysed:
Angiotensin II + H(2)O = angiotensin-(1-7) + L-phenylalanine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-230395 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Angiotensin-converting enzyme 2
Molecule details ›
Chains: A, C
Length: 826 amino acids
Theoretical weight: 95.38 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 826 amino acids
Theoretical weight: 95.38 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q9BYF1 (Residues: 2-17, 18-805; Coverage: 100%)
Sequence domains:
Sodium- and chloride-dependent transporter XTRP3
Molecule details ›
Chains: B, D
Length: 613 amino acids
Theoretical weight: 68.22 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Sodium:neurotransmitter symporter family
Length: 613 amino acids
Theoretical weight: 68.22 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: Q9NP91 (Residues: 1-592; Coverage: 100%)
Sequence domains: Sodium:neurotransmitter symporter family
