› 8i9b

Electron Microscopy
3.5Å resolution

S-ECD (Omicron BA.2.75) in complex with PD of ACE2

Released:
DOI: 10.2210/pdb8i9b/pdb
PDB entry 8i9b coloured by chain, front view.
PDB entry 8i9b coloured by chain, side view.
PDB entry 8i9b coloured by chain, top view.
Source organisms:
Entry authors: Li YN, Shen YP, Zhang YY, Yan RH
Related structures: EMD-35264

Function and Biology Details

Reaction catalysed: 
Angiotensin II + H(2)O = angiotensin-(1-7) + L-phenylalanine
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-144664 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1268 amino acids
Theoretical weight: 140.9 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-1206; Coverage: 95%)
Gene names: 2, S
Sequence domains:
Processed angiotensin-converting enzyme 2 Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 624 amino acids
Theoretical weight: 72.04 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9BYF1 (Residues: 19-615; Coverage: 76%)
Gene names: ACE2, UNQ868/PRO1885
Sequence domains: Angiotensin-converting enzyme

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 29 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-35264
Expression system: Homo sapiens

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