8j1q

Electron Microscopy
3.3Å resolution

CryoEM structure of SARS CoV-2 RBD and Aptamer complex

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-224785 (preferred)
Entry contents:
3 distinct polypeptide molecules
2 distinct DNA molecules
Macromolecules (5 distinct):
Fab Light chain (REGN10987) Chain: A
Molecule details ›
Chain: A
Length: 224 amino acids
Theoretical weight: 23.91 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Fab heavy chain (REGN10987) Chain: B
Molecule details ›
Chain: B
Length: 248 amino acids
Theoretical weight: 26.71 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Spike protein S1 Chain: C
Molecule details ›
Chain: C
Length: 253 amino acids
Theoretical weight: 28.42 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P0DTC2 (Residues: 319-541; Coverage: 18%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
AM032-0 Chain: E
Molecule details ›
Chain: E
Length: 80 nucleotides
Theoretical weight: 26.52 KDa
AM047-0 Chain: D
Molecule details ›
Chain: D
Length: 52 nucleotides
Theoretical weight: 18.03 KDa

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
Resolution: 3.3Å
Relevant EMDB volumes: EMD-35930
Expression systems:
  • Trichoplusia ni
  • Spodoptera frugiperda