› 8jew

Electron Microscopy
2.49Å resolution

Human sodium-dependent vitamin C transporter 1 bound to L-ascorbic acid in an inward-open state

Released:
DOI: 10.2210/pdb8jew/pdb
PDB entry 8jew coloured by chain, front view.
PDB entry 8jew coloured by chain, side view.
PDB entry 8jew coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Kobayashi TA, Kusakizako T, Nureki O
Related structures: EMD-36201

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-577432 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Solute carrier family 23 member 1 Chain: A
Molecule details ›
Chain: A
Length: 598 amino acids
Theoretical weight: 64.86 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9UHI7 (Residues: 1-598; Coverage: 100%)
Gene names: SLC23A1, SVCT1, YSPL3
Sequence domains: Permease family

Ligands and Environments

7 bound ligands:
Ligand ASC 1 x ASC
Ligand NA 2 x NA
Ligand AV0 2 x AV0
Ligand LBN 1 x LBN
Ligand CLR 2 x CLR
Ligand NAG 1 x NAG
Ligand PLM 1 x PLM
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.49Å
Relevant EMDB volumes: EMD-36201
Expression system: Homo sapiens

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