› 8ozp

Electron Microscopy
11.9Å resolution

In situ subtomogram average of Prototype Foamy Virus Env pentamer of trimers

Released:
DOI: 10.2210/pdb8ozp/pdb
PDB entry 8ozp coloured by chain, front view.
PDB entry 8ozp coloured by chain, side view.
PDB entry 8ozp coloured by chain, top view.
Source organism: Eastern chimpanzee simian foamy virus
Primary publication:
Integrated cryoEM structure of a spumaretrovirus reveals cross-kingdom evolutionary relationships and the molecular basis for assembly and virus entry.
Calcraft T, Stanke-Scheffler N, Nans A, Lindemann D, Taylor IA, Rosenthal PB
Cell (2024)
PMID: 39013471
Related structures: EMD-17317

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
homo 50-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-495942 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (7 distinct):
Envelope glycoprotein gp130 Chains: A, B, C, D, E, F, G, H, I, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, L
Length: 988 amino acids
Theoretical weight: 113.8 KDa
Source organism: Eastern chimpanzee simian foamy virus
Expression system: Homo sapiens
UniProt:
  • Canonical: A0A1Q1N9U9 (Residues: 1-988; Coverage: 100%)
Gene name: env
Sequence domains: Foamy virus envelope protein

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
3 bound ligands:
Ligand CLR 3 x CLR
Ligand NAG 9 x NAG
Ligand PTY 3 x PTY
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 11.9Å
Relevant EMDB volumes: EMD-17317
Expression system: Homo sapiens

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