8sb1

Electron Microscopy
4.3Å resolution

CryoEM structure of DH270.I3-CH848.10.17

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-496178 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (10 distinct):
Envelope glycoprotein gp160 Chains: A, F, K
Molecule details ›
Chains: A, F, K
Length: 471 amino acids
Theoretical weight: 52.85 KDa
Source organism: HIV-1 06TG.HT008
Expression system: Homo sapiens
UniProt:
  • Canonical: A0A1W6IPB2 (Residues: 30-495; Coverage: 55%)
Gene name: env
Sequence domains: Envelope glycoprotein GP120
Envelope glycoprotein gp160 Chains: B, G, L
Molecule details ›
Chains: B, G, L
Length: 132 amino acids
Theoretical weight: 14.73 KDa
Source organism: HIV-1 06TG.HT008
Expression system: Homo sapiens
UniProt:
  • Canonical: A0A6H1VLP0 (Residues: 460-612; Coverage: 20%)
Gene name: env
Sequence domains: Retroviral envelope protein
DH270.I3 variable heavy chain Chains: C, H, M
Molecule details ›
Chains: C, H, M
Length: 127 amino acids
Theoretical weight: 14.11 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
DH270.I3 variable light chain Chains: D, I, N
Molecule details ›
Chains: D, I, N
Length: 110 amino acids
Theoretical weight: 11.51 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.3Å
Relevant EMDB volumes: EMD-40287
Expression system: Homo sapiens