› 8tcf

Electron Microscopy
2.9Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-229855 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (5 distinct):
Integrin alpha-V heavy chain Chain: A
Molecule details ›
Chain: A
Length: 444 amino acids
Theoretical weight: 48.31 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P06756 (Residues: 31-429, 430-473; Coverage: 44%)
Gene names: ITGAV, MSK8, VNRA, VTNR
Sequence domains: FG-GAP repeat
Integrin beta-8 Chain: B
Molecule details ›
Chain: B
Length: 359 amino acids
Theoretical weight: 40.27 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P26012 (Residues: 104-467; Coverage: 49%)
Gene name: ITGB8
Sequence domains: Integrin beta chain VWA domain
Minibinder B8_BP_dslf Chain: C
Molecule details ›
Chain: C
Length: 75 amino acids
Theoretical weight: 8.58 KDa
Source organism: synthetic construct
Expression system: Escherichia coli

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
3 bound ligands:
Ligand CA 5 x CA
Ligand NAG 4 x NAG
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.9Å
Relevant EMDB volumes: EMD-41153
Expression systems:
  • Cricetulus griseus
  • Escherichia coli

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