› 8toa

Electron Microscopy
3.69Å resolution

CryoEM structure of H7 hemagglutinin from A/Shanghai2/2013 H7N9 in complex with a human neutralizing antibody H7.HK2

Released:
DOI: 10.2210/pdb8toa/pdb
PDB entry 8toa coloured by chain, front view.
PDB entry 8toa coloured by chain, side view.
PDB entry 8toa coloured by chain, top view.
Source organisms:
Entry authors: Morano NC, Becker JE, Wu X, Shapiro L
Related structures: EMD-41441

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-579346 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
H7.HK2 Neutralizing Antibody Heavy Chain Chains: A, D, H
Molecule details ›
Chains: A, D, H
Length: 119 amino acids
Theoretical weight: 13.1 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
H7.HK2 Neutralizing Antibody Light Chain Chains: B, E, L
Molecule details ›
Chains: B, E, L
Length: 112 amino acids
Theoretical weight: 12.19 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Hemagglutinin Chains: C, I, K
Molecule details ›
Chains: C, I, K
Length: 566 amino acids
Theoretical weight: 63.08 KDa
Source organism: Influenza A virus (A/Shanghai/02/2013(H7N9))
Expression system: Homo sapiens
UniProt:
  • Canonical: R4NN21 (Residues: 1-338, 339-515; Coverage: 92%)
Gene name: HA
Sequence domains: Haemagglutinin

Ligands and Environments

1 bound ligand:
Ligand NAG 11 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.69Å
Relevant EMDB volumes: EMD-41441
Expression system: Homo sapiens

Quick links