› 8u32

X-ray diffraction
2.51Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-246087 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Programmed cell death protein 1 Chains: A, D
Molecule details ›
Chains: A, D
Length: 140 amino acids
Theoretical weight: 15.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15116 (Residues: 25-146; Coverage: 46%)
Gene names: PD1, PDCD1
Sequence domains: Immunoglobulin V-set domain
Fab light chain Chains: B, E
Molecule details ›
Chains: B, E
Length: 218 amino acids
Theoretical weight: 23.51 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
Fab heavy chain Chains: C, F
Molecule details ›
Chains: C, F
Length: 229 amino acids
Theoretical weight: 24.01 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus

Ligands and Environments

1 bound ligand:
Ligand NAG 2 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P212121
Unit cell:
a: 76.482Å b: 88.881Å c: 235.859Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.195 0.23
Expression systems:
  • Escherichia coli
  • Cricetulus griseus

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