› 8ur5

Electron Microscopy
3.7Å resolution

I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-1heptad-I53_dn5 (local refinement of TH-1heptad)

Released:
DOI: 10.2210/pdb8ur5/pdb
PDB entry 8ur5 coloured by chain, front view.
PDB entry 8ur5 coloured by chain, side view.
PDB entry 8ur5 coloured by chain, top view.
Source organism: Influenza A virus
Primary publication:
Antigen spacing on protein nanoparticles influences antibody responses to vaccination.
Ellis D, Dosey A, Boyoglu-Barnum S, Park YJ, Gillespie R, Syeda H, Hutchinson GB, Tsybovsky Y, Murphy M, Pettie D, Matheson N, Chan S, Ueda G, Fallas JA, Carter L, Graham BS, Veesler D, Kanekiyo M, King NP
OpenAccess logo Cell Rep 42 113552 (2023)
PMID: 38096058
Related structures: EMD-42482

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-237637 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hemagglutinin HA1 chain Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 388 amino acids
Theoretical weight: 44.25 KDa
Source organism: Influenza A virus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q289M7 (Residues: 63-280; Coverage: 40%)
Gene name: HA
Sequence domains: Haemagglutinin

Ligands and Environments

1 bound ligand:
Ligand NAG 12 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.7Å
Relevant EMDB volumes: EMD-42482
Expression system: Homo sapiens

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