› 8vkp

Electron Microscopy
2.77Å resolution

Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with human ACE2 (focused refinement of RBD and ACE2)

Released:
DOI: 10.2210/pdb8vkp/pdb
PDB entry 8vkp coloured by chain, front view.
PDB entry 8vkp coloured by chain, side view.
PDB entry 8vkp coloured by chain, top view.
Source organisms:
Entry authors: Zhu X, Mannar D, Saville J, Poloni C, Bezeruk A, Tidey K, Ahmed S, Tuttle K, Vahdatihassani F, Cholak S, Cook L, Steiner TS, Subramaniam S
Related structures: EMD-43325

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-144194 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Spike protein S1 Chain: A
Molecule details ›
Chain: A
Length: 201 amino acids
Theoretical weight: 22.58 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
Processed angiotensin-converting enzyme 2 Chain: D
Molecule details ›
Chain: D
Length: 606 amino acids
Theoretical weight: 70.39 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 5 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.77Å
Relevant EMDB volumes: EMD-43325
Expression system: Homo sapiens

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