› 8w83

X-ray diffraction
2.82Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-518711 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
DQN0344AE02 Fab heavy chain Chains: A, E, I, M
Molecule details ›
Chains: A, E, I, M
Length: 228 amino acids
Theoretical weight: 24.57 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
DQN0344AE02 Fab light chain Chains: B, F, J, N
Molecule details ›
Chains: B, F, J, N
Length: 215 amino acids
Theoretical weight: 23.48 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
HLA class II histocompatibility antigen, DQ alpha 1 chain Chains: C, G, K, O
Molecule details ›
Chains: C, G, K, O
Length: 189 amino acids
Theoretical weight: 21.4 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P01909 (Residues: 24-206; Coverage: 79%)
Gene name: HLA-DQA1
Sequence domains:
Ig-like domain-containing protein Chains: D, H, L, P
Molecule details ›
Chains: D, H, L, P
Length: 226 amino acids
Theoretical weight: 25.85 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O19712 (Residues: 1-190; Coverage: 83%)
Gene name: HLA-DQB1
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand NAG 4 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-17A
Spacegroup: P21
Unit cell:
a: 87.488Å b: 174.235Å c: 129.656Å
α: 90° β: 93.17° γ: 90°
R-values:
R R work R free
0.28 0.278 0.321
Expression system: Homo sapiens

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