Function and Biology Details
Reaction catalysed:
Endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -(Man(GlcNAc)(2))Asn- structure. One N-acetyl-D-glucosamine residue remains attached to the protein, the rest of the oligosaccharide is released intact.
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-228491 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Endo-beta-N-acetylglucosaminidase EndoS
Molecule details ›
Chain: A
Length: 960 amino acids
Theoretical weight: 108.3 KDa
Source organism: Streptococcus pyogenes
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 960 amino acids
Theoretical weight: 108.3 KDa
Source organism: Streptococcus pyogenes
Expression system: Escherichia coli
UniProt:
- Canonical:
Q99Y92 (Residues: 37-995; Coverage: 100%)
Sequence domains:
Immunoglobulin gamma-1 heavy chain
Molecule details ›
Chains: B, C
Length: 449 amino acids
Theoretical weight: 49.39 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Length: 449 amino acids
Theoretical weight: 49.39 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical: P0DOX5 (Residues: 1-449; Coverage: 100%)
