› 8a7i

X-ray diffraction
1.76Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190676 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bromodomain-containing protein 9 Chains: A, B
Molecule details ›
Chains: A, B
Length: 113 amino acids
Theoretical weight: 13.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9H8M2 (Residues: 130-240; Coverage: 19%)
Gene names: BRD9, UNQ3040/PRO9856
Sequence domains: Bromodomain

Ligands and Environments

1 bound ligand:
Ligand L8L 2 x L8L
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21
Unit cell:
a: 36.083Å b: 66.386Å c: 55.883Å
α: 90° β: 105.83° γ: 90°
R-values:
R R work R free
0.202 0.201 0.237
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

SWI/SNF complexes in hematological malignancies: biological implications and therapeutic opportunities.
Andrades et al. (2023)
2 more