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Complex III2 from Yarrowia lipolytica, ascorbate-reduced, c-position

Source organism: Yarrowia lipolytica
Biochemical function: ubiquinol-cytochrome-c reductase activity
Biological process: mitochondrial electron transport, ubiquinol to cytochrome c
Cellular component: respiratory chain complex III

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EC 7.1.1.8: Quinol--cytochrome-c reductase

Reaction catalysed:
Quinol + 2 ferricytochrome c(Side 2) = quinone + 2 ferrocytochrome c(Side 2) + 2 H(+)(Side 2)
Systematic name:
Quinol:ferricytochrome-c oxidoreductase
Alternative Name(s):
  • CoQH(2)--cytochrome c oxidoreductase
  • Coenzyme Q--cytochrome c reductase
  • Coenzyme QH(2)--cytochrome c reductase
  • Complex III (mitochondrial electron transport)
  • Cytochrome bc1 complex
  • Dihydrocoenzyme Q--cytochrome c reductase
  • Mitochondrial electron transport complex III
  • QH(2):cytochrome c oxidoreductase
  • Reduced coenzyme Q-cytochrome c reductase
  • Reduced ubiquinone--cytochrome c oxidoreductase
  • Reduced ubiquinone--cytochrome c reductase, complex III (mitochondrial electron transport)
  • Ubihydroquinol:cytochrome c oxidoreductase
  • Ubiquinol--cytochrome c oxidoreductase
  • Ubiquinol--cytochrome c-2 oxidoreductase
  • Ubiquinol--cytochrome c1 oxidoreductase
  • Ubiquinol--cytochrome c2 reductase
  • Ubiquinol--cytochrome-c reductase
  • Ubiquinol:ferricytochrome-c oxidoreductase
  • Ubiquinone--cytochrome b-c(1) oxidoreductase
  • Ubiquinone--cytochrome c oxidoreductase
  • Ubiquinone--cytochrome-c oxidoreductase
  • Ubiquinone-cytochrome c reductase

EC 3.4.24.64: Mitochondrial processing peptidase

Reaction catalysed:
Release of N-terminal targeting peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2.
Systematic name:
-
Alternative Name(s):
  • MPP
  • Matrix peptidase
  • Matrix processing peptidase
  • Matrix processing proteinase
  • Mitochondrial protein precursor-processing proteinase
  • Processing enhancing peptidase
  • Processing enhancing peptidase (for one of two subunits)

GO terms

Sequence families

Pfam Protein families (Pfam)
PF05193
Domain description: Peptidase M16 inactive domain
Occurring in:
  1. mitochondrial processing peptidase
  2. Cytochrome b-c1 complex subunit 2, mitochondrial
The deposited structure of PDB entry 8abb contains 2 copies of Pfam domain PF05193 (Peptidase M16 inactive domain) in Mitochondrial-processing peptidase subunit beta. Showing 1 copy in chain E [auth A].
The deposited structure of PDB entry 8abb contains 2 copies of Pfam domain PF05193 (Peptidase M16 inactive domain) in Cytochrome b-c1 complex subunit 2, mitochondrial. Showing 1 copy in chain F [auth B].

PF00675
Domain description: Insulinase (Peptidase family M16)
Occurring in:
  1. mitochondrial processing peptidase
  2. Cytochrome b-c1 complex subunit 2, mitochondrial
The deposited structure of PDB entry 8abb contains 2 copies of Pfam domain PF00675 (Insulinase (Peptidase family M16)) in Mitochondrial-processing peptidase subunit beta. Showing 1 copy in chain E [auth A].
The deposited structure of PDB entry 8abb contains 2 copies of Pfam domain PF00675 (Insulinase (Peptidase family M16)) in Cytochrome b-c1 complex subunit 2, mitochondrial. Showing 1 copy in chain F [auth B].

PF09796
Domain description: Ubiquinol-cytochrome-c reductase complex subunit (QCR10)
Occurring in:
  1. Cytochrome b-c1 complex subunit 10
The deposited structure of PDB entry 8abb contains 2 copies of Pfam domain PF09796 (Ubiquinol-cytochrome-c reductase complex subunit (QCR10)) in Cytochrome b-c1 complex subunit 10. Showing 1 copy in chain J.

PF05365
Domain description: Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like
Occurring in:
  1. Complex III subunit 9
The deposited structure of PDB entry 8abb contains 2 copies of Pfam domain PF05365 (Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like) in Complex III subunit 9. Showing 1 copy in chain I.

PF02939
Domain description: UcrQ family
Occurring in:
  1. Cytochrome b-c1 complex subunit 8
The deposited structure of PDB entry 8abb contains 2 copies of Pfam domain PF02939 (UcrQ family) in Cytochrome b-c1 complex subunit 8. Showing 1 copy in chain H.

PF02271
Domain description: Ubiquinol-cytochrome C reductase complex 14kD subunit
Occurring in:
  1. Cytochrome b-c1 complex subunit 7
The deposited structure of PDB entry 8abb contains 2 copies of Pfam domain PF02271 (Ubiquinol-cytochrome C reductase complex 14kD subunit) in Cytochrome b-c1 complex subunit 7. Showing 1 copy in chain C [auth G].

PF02320
Domain description: Ubiquinol-cytochrome C reductase hinge protein
Occurring in:
  1. Ubiquinol-cytochrome C reductase hinge domain-containing protein
The deposited structure of PDB entry 8abb contains 2 copies of Pfam domain PF02320 (Ubiquinol-cytochrome C reductase hinge protein) in Ubiquinol-cytochrome C reductase hinge domain-containing protein. Showing 1 copy in chain D [auth F].

PF00355
Domain description: Rieske [2Fe-2S] domain
Occurring in:
  1. Cytochrome b-c1 complex subunit Rieske, mitochondrial
The deposited structure of PDB entry 8abb contains 2 copies of Pfam domain PF00355 (Rieske [2Fe-2S] domain) in Cytochrome b-c1 complex subunit Rieske, mitochondrial. Showing 1 copy in chain B [auth P].

PF02921
Domain description: Ubiquinol cytochrome reductase transmembrane region
Occurring in:
  1. Cytochrome b-c1 complex subunit Rieske, mitochondrial
The deposited structure of PDB entry 8abb contains 2 copies of Pfam domain PF02921 (Ubiquinol cytochrome reductase transmembrane region) in Cytochrome b-c1 complex subunit Rieske, mitochondrial. Showing 1 copy in chain B [auth P].

PF02167
Domain description: Cytochrome C1 family
Occurring in:
  1. quinol--cytochrome-c reductase
The deposited structure of PDB entry 8abb contains 2 copies of Pfam domain PF02167 (Cytochrome C1 family) in Cytochrome c domain-containing protein. Showing 1 copy in chain G [auth D].

PF00032
Domain description: Cytochrome b(C-terminal)/b6/petD
Occurring in:
  1. Cytochrome b
The deposited structure of PDB entry 8abb contains 2 copies of Pfam domain PF00032 (Cytochrome b(C-terminal)/b6/petD) in Cytochrome b. Showing 1 copy in chain A [auth C].

PF00033
Domain description: Cytochrome b/b6/petB
Occurring in:
  1. Cytochrome b
The deposited structure of PDB entry 8abb contains 2 copies of Pfam domain PF00033 (Cytochrome b/b6/petB) in Cytochrome b. Showing 1 copy in chain A [auth C].

InterPro InterPro annotations
IPR002326
Domain description: Cytochrome c1
Occurring in:
  1. quinol--cytochrome-c reductase
IPR011249
Domain description: Metalloenzyme, LuxS/M16 peptidase-like
Occurring in:
  1. mitochondrial processing peptidase
  2. Cytochrome b-c1 complex subunit 2, mitochondrial
IPR003197
Domain description: Cytochrome b-c1 complex subunit 7
Occurring in:
  1. Cytochrome b-c1 complex subunit 7
IPR005805
Domain description: Rieske iron-sulphur protein, C-terminal
Occurring in:
  1. Cytochrome b-c1 complex subunit Rieske, mitochondrial
IPR005798
Domain description: Cytochrome b/b6, C-terminal
Occurring in:
  1. Cytochrome b
IPR005797
Domain description: Cytochrome b/b6, N-terminal domain
Occurring in:
  1. Cytochrome b
IPR019182
Domain description: Cytochrome b-c1 complex subunit 10, fungi
Occurring in:
  1. Cytochrome b-c1 complex subunit 10
IPR008027
Domain description: Cytochrome b-c1 complex subunit 9
Occurring in:
  1. Complex III subunit 9
IPR036656
Domain description: Cytochrome b-c1 complex subunit 9 superfamily
Occurring in:
  1. Complex III subunit 9
IPR004205
Domain description: Cytochrome b-c1 complex subunit 8
Occurring in:
  1. Cytochrome b-c1 complex subunit 8
IPR036642
Domain description: Cytochrome b-c1 complex subunit 8 superfamily
Occurring in:
  1. Cytochrome b-c1 complex subunit 8
IPR036544
Domain description: Cytochrome b-c1 complex subunit 7 superfamily
Occurring in:
  1. Cytochrome b-c1 complex subunit 7
IPR036811
Domain description: Ubiquinol-cytochrome C reductase hinge domain superfamily
Occurring in:
  1. Ubiquinol-cytochrome C reductase hinge domain-containing protein
IPR017941
Domain description: Rieske [2Fe-2S] iron-sulphur domain
Occurring in:
  1. Cytochrome b-c1 complex subunit Rieske, mitochondrial
IPR036922
Domain description: Rieske [2Fe-2S] iron-sulphur domain superfamily
Occurring in:
  1. Cytochrome b-c1 complex subunit Rieske, mitochondrial
IPR036909
Domain description: Cytochrome c-like domain superfamily
Occurring in:
  1. quinol--cytochrome-c reductase
IPR007863
Domain description: Peptidase M16, C-terminal
Occurring in:
  1. mitochondrial processing peptidase
  2. Cytochrome b-c1 complex subunit 2, mitochondrial
IPR011765
Domain description: Peptidase M16, N-terminal
Occurring in:
  1. mitochondrial processing peptidase
  2. Cytochrome b-c1 complex subunit 2, mitochondrial
IPR023184
Domain description: Ubiquinol-cytochrome C reductase hinge domain
Occurring in:
  1. Ubiquinol-cytochrome C reductase hinge domain-containing protein
IPR006317
Domain description: Ubiquinol-cytochrome c reductase, iron-sulphur subunit
Occurring in:
  1. Cytochrome b-c1 complex subunit Rieske, mitochondrial
IPR014349
Domain description: Rieske iron-sulphur protein
Occurring in:
  1. Cytochrome b-c1 complex subunit Rieske, mitochondrial
IPR004192
Domain description: Cytochrome b-c1 complex subunit Rieske, transmembrane domain
Occurring in:
  1. Cytochrome b-c1 complex subunit Rieske, mitochondrial
IPR037008
Domain description: Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily
Occurring in:
  1. Cytochrome b-c1 complex subunit Rieske, mitochondrial
IPR021157
Domain description: Cytochrome c1, transmembrane anchor, C-terminal
Occurring in:
  1. quinol--cytochrome-c reductase
IPR009056
Domain description: Cytochrome c-like domain
Occurring in:
  1. quinol--cytochrome-c reductase
IPR036150
Domain description: Cytochrome b/b6, C-terminal domain superfamily
Occurring in:
  1. Cytochrome b
IPR016174
Domain description: Di-haem cytochrome, transmembrane
Occurring in:
  1. Cytochrome b
IPR030689
Domain description: Cytochrome b
Occurring in:
  1. Cytochrome b
IPR027387
Domain description: Cytochrome b/b6-like domain superfamily
Occurring in:
  1. Cytochrome b
IPR001431
Domain description: Peptidase M16, zinc-binding site
Occurring in:
  1. Cytochrome b-c1 complex subunit 2, mitochondrial

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