› 8afo

X-ray diffraction
1.99Å resolution

Structure of fibronectin 2 and 3 of L1CAM at 2.0 Angstrom

Released:
DOI: 10.2210/pdb8afo/pdb
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PDB entry 8afo coloured by chain, front view.
PDB entry 8afo coloured by chain, side view.
PDB entry 8afo coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
X-ray structure and function of fibronectin domains two and three of the neural cell adhesion molecule L1.
Guédez G, Loers G, Jeffries CM, Kozak S, Meijers R, Svergun DI, Schachner M, Löw C
FASEB J 37 e22823 (2023)
PMID: 36809668

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-273548 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Neural cell adhesion molecule L1 Chain: A
Molecule details ›
Chain: A
Length: 216 amino acids
Theoretical weight: 24.38 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P32004 (Residues: 712-917; Coverage: 17%)
Gene names: CAML1, L1CAM, MIC5
Sequence domains: Fibronectin type III domain

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 4 x NAG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)
Spacegroup: C2221
Unit cell:
a: 56.083Å b: 96.749Å c: 105.853Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.193 0.239
Expression system: Homo sapiens

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Citations

1 review citation

Engineering cell-derived extracellular matrix for peripheral nerve regeneration.
Xu et al. (2024)
1 other article

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