› 8ag3

Electron Microscopy
3.47Å resolution

Vaccinia C16 N-terminal domains

Released:
DOI: 10.2210/pdb8ag3/pdb
PDB entry 8ag3 coloured by chain, front view.
PDB entry 8ag3 coloured by chain, side view.
PDB entry 8ag3 coloured by chain, top view.
Source organism: Vaccinia virus Western Reserve
Primary publication:
Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus.
Rivera-Calzada A, Arribas-Bosacoma R, Ruiz-Ramos A, Escudero-Bravo P, Boskovic J, Fernandez-Leiro R, Oliver AW, Pearl LH, Llorca O
Nat Commun 13 7062 (2022)
PMID: 36400800
Related structures: EMD-15414

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136687 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein C10 Chains: C, D
Molecule details ›
Chains: C, D
Length: 369 amino acids
Theoretical weight: 42.48 KDa
Source organism: Vaccinia virus Western Reserve
Expression system: Escherichia coli
UniProt:
  • Canonical: P03296 (Residues: 1-331; Coverage: 100%)
Gene names: C10L, VACWR010, VACWR209
Sequence domains: Poxvirus C4/C10 protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.47Å
Relevant EMDB volumes: EMD-15414
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

Exaptation of Inactivated Host Enzymes for Structural Roles in Orthopoxviruses and Novel Folds of Virus Proteins Revealed by Protein Structure Modeling.
Mutz et al. (2023)
2 more

1 mention without citation

Identification of core therapeutic targets for Monkeypox virus and repurposing potential of drugs against them: An in silico approach.
Sahu et al. (2023)