PDB 8age structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Reaction catalysed:

Dolichyl diphosphooligosaccharide + [protein]-L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine

Biochemical function:

protein binding

Biological process:

protein N-linked glycosylation

Cellular component:

membrane

Sequence domains:

1 more domain

Structure analysis Details

Assembly composition:

hetero nonamer (preferred)

Assembly name:

Oligosaccharyl transferase complex, OST3 variant and peptide (preferred)

PDBe Complex ID:

PDB-CPX-221232 (preferred)

Entry contents:

9 distinct polypeptide molecules

Macromolecules (11 distinct):

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3 Chain: A

Molecule details ›

Chain: A
Length: 718 amino acids
Theoretical weight: 81.6 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:

Canonical: P39007 (Residues: 1-718; Coverage: 100%)

Gene names: STT3, YGL022W
Sequence domains:

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST4 Chain: B

Molecule details ›

Chain: B
Length: 65 amino acids
Theoretical weight: 6.87 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:

Canonical: Q99380 (Residues: 1-36; Coverage: 100%)

Gene names: OST4, YDL232W
Sequence domains: Oligosaccaryltransferase

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST5 Chain: C

Molecule details ›

Chain: C
Length: 86 amino acids
Theoretical weight: 9.53 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:

Canonical: Q92316 (Residues: 1-86; Coverage: 100%)

Gene names: OST5, YGL226BC, YGL226C-A
Sequence domains: Oligosaccharyltransferase subunit 5

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2 Chain: D

Molecule details ›

Chain: D
Length: 130 amino acids
Theoretical weight: 14.71 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:

Canonical: P46964 (Residues: 1-130; Coverage: 100%)

Gene names: OST2, YOR103C, YOR3211C
Sequence domains: DAD family

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 Chain: E

Molecule details ›

Chain: E
Length: 476 amino acids
Theoretical weight: 54.12 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:

Canonical: P41543 (Residues: 1-476; Coverage: 100%)

Gene names: J1404, NLT1, OST1, YJL002C
Sequence domains: Ribophorin I

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1 Chain: F

Molecule details ›

Chain: F
Length: 283 amino acids
Theoretical weight: 31.34 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:

Canonical: Q02795 (Residues: 1-283; Coverage: 99%)

Gene names: SWP1, YM9375.19, YMR149W
Sequence domains: Oligosaccharyltransferase subunit Ribophorin II

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1 Chain: G

Molecule details ›

Chain: G
Length: 430 amino acids
Theoretical weight: 49.44 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:

Canonical: P33767 (Residues: 1-430; Coverage: 100%)

Gene names: WBP1, YEL002C
Sequence domains: Oligosaccharyltransferase 48 kDa subunit beta

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3 Chain: H

Molecule details ›

Chain: H
Length: 350 amino acids
Theoretical weight: 39.52 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:

Canonical: P48439 (Residues: 1-350; Coverage: 100%)

Gene names: OST3, YOR085W, YOR3124W
Sequence domains: OST3 / OST6 family, transporter family

PEPTIDE Chain: P

Molecule details ›

Chain: P
Length: 7 amino acids
Theoretical weight: 697 Da
Source organism: Saccharomyces cerevisiae
Expression system: Not provided