8agw

Electron Microscopy
2.6Å resolution

Yeast RQC complex in state D

Released:

Function and Biology Details

Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero 53-mer (preferred)
PDBe Complex ID:
PDB-CPX-272123 (preferred)
Entry contents:
48 distinct polypeptide molecules
4 distinct RNA molecules
Macromolecules (52 distinct):
Large ribosomal subunit protein eL15A Chain: A
Molecule details ›
Chain: A
Length: 204 amino acids
Theoretical weight: 24.48 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P05748 (Residues: 1-204; Coverage: 100%)
Gene names: RPL10A, RPL13A, RPL15A, YL10A, YLR029C
Sequence domains: Ribosomal L15
Large ribosomal subunit protein uL13A Chain: B
Molecule details ›
Chain: B
Length: 199 amino acids
Theoretical weight: 22.25 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P26784 (Residues: 1-199; Coverage: 100%)
Gene names: RPL13, RPL16A, RPL21A, YIL133C
Sequence domains: Ribosomal protein L13
Large ribosomal subunit protein uL22A Chain: C
Large ribosomal subunit protein eL18A Chain: D
Large ribosomal subunit protein eL19A Chain: E
Large ribosomal subunit protein eL20A Chain: F
Large ribosomal subunit protein eL21A Chain: G
Large ribosomal subunit protein eL22A Chain: H
Large ribosomal subunit protein uL14A Chain: I
Large ribosomal subunit protein eL24A Chain: J
Large ribosomal subunit protein uL23 Chain: K
Large ribosomal subunit protein uL24A Chain: L
Large ribosomal subunit protein eL27A Chain: M
Large ribosomal subunit protein uL15 Chain: N
Large ribosomal subunit protein eL29 Chain: O
Large ribosomal subunit protein eL30 Chain: P
Large ribosomal subunit protein eL31A Chain: Q
Large ribosomal subunit protein eL32 Chain: R
Large ribosomal subunit protein eL33A Chain: S
Large ribosomal subunit protein eL34A Chain: T
Large ribosomal subunit protein uL29A Chain: U
Large ribosomal subunit protein eL36A Chain: V
Large ribosomal subunit protein eL37A Chain: W
Large ribosomal subunit protein eL38 Chain: X
Large ribosomal subunit protein eL39 Chain: Y
Ubiquitin-ribosomal protein eL40A fusion protein Chain: Z
Large ribosomal subunit protein eL42A Chain: b
Large ribosomal subunit protein eL43A Chain: c
Small ribosomal subunit protein eS32A Chain: d
Large ribosomal subunit protein uL2A Chain: j
Large ribosomal subunit protein uL3 Chain: k
Large ribosomal subunit protein uL4A Chain: l
Large ribosomal subunit protein uL18 Chain: m
Large ribosomal subunit protein eL6B Chain: n
Large ribosomal subunit protein uL30A Chain: o
Large ribosomal subunit protein eL8A Chain: p
Large ribosomal subunit protein uL6A Chain: q
Large ribosomal subunit protein uL16 Chain: r
Large ribosomal subunit protein uL5A Chain: s
Large ribosomal subunit protein eL13A Chain: t
Large ribosomal subunit protein eL14A Chain: u
Ribosome quality control complex subunit 2 Chain: a
E3 ubiquitin-protein ligase listerin Chain: e
Eukaryotic translation initiation factor 6 Chain: g
Large ribosomal subunit protein uL11A Chain: z
Large ribosomal subunit protein uL10 Chain: 0
CAT-tailed nascent peptide Chain: 1
Large ribosomal subunit protein uL1A Chain: w
25S ribosomal RNA Chain: f
5S ribosomal RNA Chain: h
5.8S ribosomal RNA Chain: i
Ala tRNA Chains: x, y

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.6Å
Relevant EMDB volumes: EMD-15426