› 8ahc

X-ray diffraction
1.5Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190676 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bromodomain-containing protein 9 Chains: A, B
Molecule details ›
Chains: A, B
Length: 123 amino acids
Theoretical weight: 14.25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H8M2 (Residues: 134-243; Coverage: 18%)
  • Best match: Q9H8M2-1 (Residues: 14-134)
Gene names: BRD9, UNQ3040/PRO9856
Sequence domains: Bromodomain

Ligands and Environments

1 bound ligand:
Ligand M2O 2 x M2O
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P21212
Unit cell:
a: 69.883Å b: 125.201Å c: 29.463Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.211 0.23
Expression system: Escherichia coli

Quick links

Citations

2 citation in other articles

An alternative NURF complex sustains acute myeloid leukemia by regulating the accessibility of insulator regions.
Radzisheuskaya et al. (2023)
1 more