Crystal structure of the Q65A mutant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa cocrystallized with adenosine in the presence of K+ cations
Source organism:
Pseudomonas aeruginosa PAO1
Biochemical function:
hydrolase activity
Biological process: L-homocysteine biosynthetic process
Cellular component: cytosol
Biological process: L-homocysteine biosynthetic process
Cellular component: cytosol
Protein families (Pfam)![The deposited structure of PDB entry 8aju contains 4 copies of Pfam domain PF05221 (S-adenosyl-L-homocysteine hydrolase) in Adenosylhomocysteinase. Showing 2 copies in chain A [auth AAA].](https://www.ebi.ac.uk/pdbe/static/entry/8aju_1_AAA_Pfam_PF05221_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>8aju</span> contains 4 copies of Pfam domain <span class='highlight'>PF05221 (S-adenosyl-L-homocysteine hydrolase)</span> in <span class='highlight'>Adenosylhomocysteinase</span>. Showing 2 copies in chain <span class='highlight'>A [auth AAA]</span>.")
![The deposited structure of PDB entry 8aju contains 2 copies of Pfam domain PF00670 (S-adenosyl-L-homocysteine hydrolase, NAD binding domain) in Adenosylhomocysteinase. Showing 1 copy in chain A [auth AAA].](https://www.ebi.ac.uk/pdbe/static/entry/8aju_1_AAA_Pfam_PF00670_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>8aju</span> contains 2 copies of Pfam domain <span class='highlight'>PF00670 (S-adenosyl-L-homocysteine hydrolase, NAD binding domain)</span> in <span class='highlight'>Adenosylhomocysteinase</span>. Showing 1 copy in chain <span class='highlight'>A [auth AAA]</span>.")