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PD-1 extracellular domain in complex with Fab fragment from D12 antibody

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: negative regulation of immune response
Cellular component: membrane

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GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF07686
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. Programmed cell death protein 1
The deposited structure of PDB entry 8as0 contains 8 copies of Pfam domain PF07686 (Immunoglobulin V-set domain) in Programmed cell death protein 1. Showing 1 copy in chain F.

InterPro InterPro annotations
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. Programmed cell death protein 1
  2. D12 antibody heavy chain, Fab fragment
  3. D12 antibody light chain, Fab fragment
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. Programmed cell death protein 1
  2. D12 antibody heavy chain, Fab fragment
  3. D12 antibody light chain, Fab fragment
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. Programmed cell death protein 1
  2. D12 antibody heavy chain, Fab fragment
  3. D12 antibody light chain, Fab fragment
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. Programmed cell death protein 1
  2. D12 antibody heavy chain, Fab fragment
  3. D12 antibody light chain, Fab fragment
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. D12 antibody heavy chain, Fab fragment
  2. D12 antibody light chain, Fab fragment
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. Programmed cell death protein 1
  2. D12 antibody heavy chain, Fab fragment
  3. D12 antibody light chain, Fab fragment
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. D12 antibody heavy chain, Fab fragment
  2. D12 antibody light chain, Fab fragment
IPR042379
Domain description: Programmed cell death protein 1
Occurring in:
  1. Programmed cell death protein 1

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