› 8ax8

X-ray diffraction
1.55Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-223133 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Apolipoprotein E; Maltose/maltodextrin-binding periplasmic protein Chain: A
Molecule details ›
Chain: A
Length: 675 amino acids
Theoretical weight: 75.12 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: P0AEX9 (Residues: 24-392; Coverage: 99%)
  • Canonical: P02649 (Residues: 19-317; Coverage: 100%)
Gene names: APOE, JW3994, b4034, malE
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P3121
Unit cell:
a: 47.693Å b: 47.693Å c: 104.773Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.198 0.231
Expression system: Escherichia coli

Quick links

Citations

2 citation in other articles

Biochemical evidence for conformational variants in the anti-viral and pro-metastatic protein IFITM1.
Nekulová et al. (2024)
1 more

1 mention without citation

Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer's Disease drug candidate.
Nemergut et al. (2023)