PDB 8ayl structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Biochemical function:

signaling receptor activity

Biological process:

monoatomic ion transport

Cellular component:

membrane

Sequence domains:

1 more domain

Structure analysis Details

Assembly composition:

hetero hexamer (preferred)

Assembly name:

GluA1-GluA2 AMPA receptor complex and Voltage-dependent calcium channel gamma-8 subunit (preferred)

PDBe Complex ID:

PDB-CPX-148600 (preferred)

Entry contents:

3 distinct polypeptide molecules

Macromolecules (3 distinct):

Glutamate receptor 2 Chains: B, D

Molecule details ›

Chains: B, D
Length: 860 amino acids
Theoretical weight: 96.25 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:

Canonical: P19491 (Residues: 1-860; Coverage: 97%)
Best match: P19491-2 (Residues: 1-860)

Gene names: GluA2, Glur2, Gria2
Sequence domains:

Voltage-dependent calcium channel gamma-8 subunit Chains: I, J

Molecule details ›

Chains: I, J
Length: 423 amino acids
Theoretical weight: 43.58 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:

Canonical: Q8VHW5 (Residues: 2-417; Coverage: 99%)

Gene name: Cacng8
Sequence domains: PMP-22/EMP/MP20/Claudin family

Glutamate receptor 1 Chains: A, C

Molecule details ›

Chains: A, C
Length: 915 amino acids
Theoretical weight: 102.66 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:

Canonical: P19490 (Residues: 1-19, 20-907; Coverage: 100%)
Best match: P19490-2 (Residues: 1-19, 20-907)